Category Archives: Critical care

Pharmacokinetics in critical care: PowerPoint presentation

This presentation entitled “Applied Pharmacokinetics in the Adult Critically Ill” is oriented to show pharmacokinetics concepts that are relevant to the ICU. Some of them are:

Pharmacotherapy in critical care: pharmacokinetics

Recommended pharmacokinetics reading

  • Pocket Guide: Pharmacokinetics Made Easy (2009)
  • Basic Clinical Pharmacokinetics (2009)
  • Concepts in Clinical Pharmacokinetics (2010)
  • Clinical Pharmacokinetics, 4th Edition (2008)
  • Xigris (Drotrecogin alfa activated): concerns of serious bleeding and increased death trigger FDA safety review

    On February 4th, 2009 the FDA announced an ongoing safety review of Xigris (Drotrecogin alfa [activated]). An introduction from Wikipedia: Drotrecogin alfa (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C ( rhAPC) that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties. Drotrecogin alpha (activated) belongs to the class…

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