Category Archives: Pharmacokinetics

Geriatric pharmacology: pharmacokinetics, polypharmacy and related topics

Posted on May 8, 2010 by Flavio Guzmán, MD • 0 Comments

Collection of different PowerPoint presentations on pharmacological concepts relevant to drug therapy in the geriatric population.… Continue Reading

Filed Under: Featured, Pharmacodynamics, Pharmacokinetics, PowerPoint presentations

Video on aspirin pharmacokinetics: the role of the ion trapping phenomenon

Posted on April 19, 2010 by Flavio Guzmán, MD • 0 Comments

Pharmacology video animation on aspirin (ASA) pharmacokinetics. It depicts how pH influences the gastric absorption of aspirin.… Continue Reading

Filed Under: NSAIDS, Pharmacokinetics, Videos

Pharmacokinetics in critical care: PowerPoint presentation

Posted on January 6, 2010 by Flavio Guzmán, MD • 1 Comment

This presentation entitled “Applied Pharmacokinetics in the Adult Critically Ill” is oriented to show pharmacokinetics concepts that are relevant to the ICU. Some of them are: First pass metabolism Patients in whom oral administration should be avoided P-glycoprotein (P-gp) Relevance of drug distribution in compartments Context specific half life Cytochrome 450 Pharmacogenetics Pharmacotherapy in critical… Continue Reading

Filed Under: Critical care, Featured, Pharmacokinetics

Pharmacokinetics video and PowerPoint: volume of distribution and factors that affect it

Posted on March 27, 2009 by Flavio Guzmán, MD • 6 Comments

Video showing determinants of drug distribution: protein binding, molecular weight, lipid solubility. PowerPoint slideshow analizing the meaning of volume of distribution.… Continue Reading

Filed Under: Pharmacokinetics, Pharmacology animations, Videos

Pharmacokinetics study aid: charts, equations and definitions

Posted on February 18, 2009 by Flavio Guzmán, MD • 0 Comments

Study aids by the Department of Pharmacology at University of Utah. Clearance, Volume of distribution, loading dose, maintenance dose.… Continue Reading

Filed Under: Flash cards, Pharmacokinetics

Half life of drugs. Video lecture for nurses

Posted on January 18, 2009 by Flavio Guzmán, MD • 3 Comments

This video lecture has as target audience RN’s, it explains a core concept: half life of drugs and its relevance to nurses. More on nursing pharmacology Recommended pharmacokinetics reading Pocket Guide: Pharmacokinetics Made Easy (2009) Basic Clinical Pharmacokinetics (2009) Concepts in Clinical Pharmacokinetics (2010) Clinical Pharmacokinetics, 4th Edition (2008)… Continue Reading

Filed Under: Pharmacokinetics

Pharmacokinetics: Intramuscular injection administration. Video animation

Posted on January 18, 2009 by Flavio Guzmán, MD • 0 Comments

Recommended pharmacokinetics reading Pocket Guide: Pharmacokinetics Made Easy (2009) Basic Clinical Pharmacokinetics (2009) Concepts in Clinical Pharmacokinetics (2010) Clinical Pharmacokinetics, 4th Edition (2008)… Continue Reading

Filed Under: Pharmacokinetics, Pharmacology animations

USMLE-like pharmacology quiz. Part 3: pharmacokinetics (drug metabolism)

Posted on January 12, 2009 by Flavio Guzmán, MD • 0 Comments

The following are multiple choice questions in a style similar to those included in the USMLE step 1. The main topic here is: pharmacokinetics (drug metabolism). This quiz has been uploaded to Scribd by medical student James Lamberg. The correct answers can be found in link at the end of this post. Note: the words… Continue Reading

Filed Under: MCQs and quizzes for USMLE, Pharmacokinetics

Definition of half life of drugs

Posted on January 10, 2009 by Flavio Guzmán, MD • 0 Comments

What is half life in pharmacokinetics? A pharmacological definition and an analysis to its formula.… Continue Reading

Filed Under: Pharmacokinetics

Absorption rate constant (ka) definition

Posted on January 8, 2009 by Flavio Guzmán, MD • 0 Comments

Absorption rate constant (ka), a pharmacokinetic definition.… Continue Reading

Filed Under: Definitions, Pharmacokinetics

Infusion kinetics definition

Posted on January 8, 2009 by Flavio Guzmán, MD • 0 Comments

The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Infusion Kinetics: Infusion, as a means of drug administration, involves an effectively continuous flow of a drug solution into the blood stream over a relatively long period of time. (Intravascular injections are separate administrations… Continue Reading

Filed Under: Definitions, Pharmacokinetics

Pharmacology mnemonic: drugs that induce enzymatic metabolism

Posted on January 6, 2009 by Flavio Guzmán, MD • 0 Comments

Metabolism enzyme inducers “Randy’s Black Car Goes Putt Putt and Smokes “: Rifampin Barbiturates Carbamazepine Grisoefulvin Phenytoin Phenobarb Smoking cigarettes Thanks to MedExcel… Continue Reading

Filed Under: Mnemonics, Pharmacokinetics

Pharmacology glossary. Dose duration curve definition

Posted on January 1, 2009 by Flavio Guzmán, MD • 0 Comments

The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Dose-Duration Curve: The curve describing the relationship between dose (as the independent variable) and duration of drug effect (as the dependent variable, T). The slope of the curve is always positive, in contrast to… Continue Reading

Filed Under: Definitions, Pharmacodynamics, Pharmacokinetics

Pharmacokinetics video animation. IV administration.

Posted on December 31, 2008 by Flavio Guzmán, MD • 0 Comments

Recommended pharmacokinetics reading Pocket Guide: Pharmacokinetics Made Easy (2009) Basic Clinical Pharmacokinetics (2009) Concepts in Clinical Pharmacokinetics (2010) Clinical Pharmacokinetics, 4th Edition (2008)… Continue Reading

Filed Under: Pharmacokinetics