Category Archives: Rheumatology

Ibandronic acid (Bondronat) for the treatment of hypercalcaemia and bony metastases. Australian Prescriber review

From Australian Prescriber: Ibandronic acid Bondronat (Hospira) vials containing 6 mg/6 mL Approved indications: hypercalcaemia, bony metastases of breast cancer Australian Medicines Handbook section 10.3.1 Bisphosphonates can reduce the hypercalcaemia of malignant disease by inhibiting the resorption of bone. Clodronate, pamidronate and zoledronic acid are already available for this indication. They are nowContinue Reading

CHMP positive opinion for lasofoxifene (Fablyn), a new SERM

Press release about the positive opinion of the CHMP for Fablyn (lasofoxifene): COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE  SUMMARY OF POSITIVE OPINION for FABLYN International Nonproprietary Name (INN): lasofoxifene On 18 December 2008  the Committee for Medicinal Products  for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing authorisation for the…Continue Reading

NSAIDS risks and benefits podcast

This week Therapeutics initative podcast deals with NSAIDS: NSAIDS: Considering the Risks and Benefits (Therapeutics Initiative Podcast – December 10th) In our 33rd episode we follow-up our discussion of osteoarthritis by examining the risks and benefits of oral anti-inflammatories including Cox-2 inhibitors. We review the effects on pain relief and the theory of anti-inflammation. We…Continue Reading

Osteoarthritis treatment podcast: NSAIDs, opioids, glucosamine and other therapies

In this podcast, the team of Therapeutics Initiative  reviews the pharmacological and non pharmacological treatments for osteoarthritis. “In our 32nd episode we review the therapeutic options for the treatment of osteoarthritis. We first deal with lifestyle interventions for osteoarthritis. We consider the pain pharmaceuticals like acetaminophen, topical or oral NSAIDs, and opiates as well as…

Zoledronic acid: summary review and side effects profile published on the NPS RADAR

An excerpt of the summary review and side effects profile of Zoledronic acid, published on the australian NPS RADAR: Zoledronic acid is an intravenous bisphosphonate. It is given as a once-yearly infusion for osteoporosis in women with any fracture, and in men with a minimal-trauma hip fracture. Some patients may prefer zoledronic acid to oral…Continue Reading

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