Heparins PowerPoint presentation
PPT discussing chemistry, mechanism of action, classification,pharmacokinetics and clinical uses of heparin.
Warfarin PowerPoint presentation
PPT on Warfarin pharmacotherapy. Discusses mechanism of action, dosing and target INRs, drug and food interactions, and patient counseling.
Alpha receptors
Alpha adrenergic receptors location and effects highlighted in pharmacology charts.
The coagulation cascade
Coagulation cascade: several resources (videos, animations and tutorials) depicting coagulation factors and pathways.
PPI – Clopidogrel (Plavix) interaction: the latest news
Clopidogrel (Plavix) and PPIs resource center: updates on the possible interaction between omeprazole and clopidogrel.
Thrombolytic agents: mechanism of action, indications, contraindications and side effects
Thrombolytic agents are used to lyse already formed blood clots in clinical settings where ischemia may be fatal ( acute mycardial infarction, pulmonary embolism, ischemic stroke, and arterial thrombosis). Very precise indications rule the use of these drugs, which are not free from serious side effects ( bleeding). Outline: Mechanism of action of thrombolytic therapy […]
Hypertension management: pharmacotherapy lecture notes (PDF)
Phharmacological management of hypertension: by the Pharmacology OpenCourseWare initiative at Harvard Medical School – MIT.
COGENT trial: no clopidogrel-PPIs interaction
According to the results of the COGENT trial, the combination of the antiplatelet clopidogrel and the PPI omeprazole does not produce clinically relevant cardiovascular interactions.
Antiplatelet agents: mechanisms of action and general overview
This post is an overview on antiplatelet drugs, we will focus on the classification of agents and their mechanism of action. The most relevant facts related to therapeutics will also be discussed here, followed by a video review by K.G. Paul, M.D. A related article explores the pharmacology of thrombolytic agents. Classification of antiplatelet agents […]
Video lecture: cholesterol-lowering agents mechanisms of action
Video lecture on the different classes of drugs used as lipid-lowering agents. Features an overview on their main characteristics as well as their mechanisms of action.
Prasugrel (Effient): mechanism of action, indications and adverse effects
Overview on the mechanism of action, indications, adverse effects profile of prasugrel (Efient in the EU, Effient in the USA). PowerPoint on the TIMI TRITON 38 trial.
ACE inhibitors and angiotensin II receptor blockers should be avoided in pregnancy and during breastfeeding
UK’s MHRA: do not to use ACE inhibitors and angiotensin II receptor antagonists while breastfeeding. Hypertension Journal reviews ACEI toxicity in pregnancy.
Animation on coagulation physiology and the mechanism of action of glycoprotein IIb/IIIa antagonists
Animation on coagulation physiology and mechanism of action of Gp IIb/IIIa inhibitors (abciximab, eptifibatide and tirofiban) and other antiplatelet drugs.
PowerPoint lectures on pharmacology of antiarrythmic drugs. From pathophysiology to therapeutics
PowerPoint lectures on the pharmacology of antiarrythmic drugs: mechanism of action, indications, Vaughan-Williams classification,