Benzodiazepines mechanism of action

Benzodiazepines and GABA receptors: an animation on their mechanism of action Gamma amino butyric acid (GABA) is an inhibiting neurotransmitter that is present on human brains. As shown in the animation, gamma amino butyric acid promotes opening of a postsynaptic receptor, the GABA-A receptor. This opening leads to a increased conductance to cloride ions, which […]

MCQs for USMLE review on psychopharmacology: antipsychotics, benzodiazepines, antidepressants and lithium

These pharmacology MCQs from the UMKC School of Medicine have a different degree of difficulty, but are useful to review pharmacology of psychotropics. Psychotropics Item Number: 11667 correct answer: 4 category: Psychotropics 1. The symptoms of tardive dyskinesia will acutely improve with: 1. administration of diphenhydramine 2. administration of amantadine 3. administration of bromocriptine 4. […]

Risk of midazolam overdose: NHS alert

This is a rapid response report from the National Patient Safety Agency (A branch of NHS) about the risk of midazolam (Dormicum, Hypnovel, Midacum and Versed) overdose Reducing risk of overdose with midazolam injection in adults Issue Some adult patients are being overdosed with midazolam injection when used for conscious sedation. TheĀ presentation of high strength […]

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