Pharmacology education for healthcare professionalshttps://pharmacologycorner.com/https://pharmacologycorner.com/mania-in-bipolar-disorder-a-new-patient-guide/https://pharmacologycorner.com/mania-in-bipolar-disorder-a-new-patient-guide/A new article for patients on mania has been published on the Psych Education website. Mania, defined by extreme energy levels and fluctuating emotions, can cause considerable disruptions in a patient’s life. This article translates the DSM-5 diagnostic criteria for mania into layman’s terms, useful for patients unfamiliar with the medical terminology. The article includesTue, 23 Jan 2024 00:42:28 GMThttps://pharmacologycorner.com/new-article-fluvoxamine-practical-guide/https://pharmacologycorner.com/new-article-fluvoxamine-practical-guide/The Psychopharmacology Institute has published an essential guide for prescribers on the use of fluvoxamine. Below some key points. Check out the full guide for more details on using fluvoxamine in your practice: Fluvoxamine Practical Guide: Pharmacology, Indications, Dosing Guidelines, and Adverse EffectsFri, 29 Sep 2023 12:49:07 GMThttps://pharmacologycorner.com/new-article-fluoxetine-pharmacology-and-practical-prescribing-guide/https://pharmacologycorner.com/new-article-fluoxetine-pharmacology-and-practical-prescribing-guide/A new fluoxetine prescribing guide has just been published at the Psychopharmacology Institute. This comprehensive article reviews the pharmacology, indications, dosing, side effects, and special considerations for using fluoxetine. Key points: Fluoxetine Practical Guide: Pharmacology, Indications, Dosing Guidelines and Adverse EffectsTue, 12 Sep 2023 14:53:57 GMThttps://pharmacologycorner.com/a-deep-dive-into-citalopram-and-escitalopram/https://pharmacologycorner.com/a-deep-dive-into-citalopram-and-escitalopram/The Psychopharmacology Institute has recently published a comprehensive article on citalopram and escitalopram. This article is a must-read for clinicians who want to deepen their understanding of these two commonly prescribed antidepressants. Some pearls extracted from the article: Here’s what you can expect to learn: Citalopram and Escitalopram: A Summary of Key Differences and SimilaritiesSat, 26 Aug 2023 01:27:14 GMThttps://pharmacologycorner.com/new-psychiatry-and-psychopharmacology-podcast/https://pharmacologycorner.com/new-psychiatry-and-psychopharmacology-podcast/Our partners at the Psychopharmacology Institute have recently released a podcast discussing psychiatry and psychopharmacology updates. We are sure you will find this useful, the episodes are very well edited and to the point. Click one of the links below to subscribe : Apple podcasts Google podcasts Stitcher Spotify RSS (other podcasting apps)Tue, 21 Aug 2018 16:21:24 GMThttps://pharmacologycorner.com/new-psychiatry-guidelines-bipolar-disorder/https://pharmacologycorner.com/new-psychiatry-guidelines-bipolar-disorder/The Psychopharmacology Institute has created a compilation of guidelines on bipolar disorder. This includes guidelines from: NICE, BAP, WFSBP and CANMAT. Find more here: Bipolar Disorder Treatment GuidelinesFri, 25 Mar 2016 14:51:36 GMThttps://pharmacologycorner.com/new-depot-antipsychotics/https://pharmacologycorner.com/new-depot-antipsychotics/New long-acting (depot) antipsychotics were approved in 2015: Aristada and Invega Trinza. This practical guide from the Psychopharmacology Institute summarizes the essentials for prescribers. Long-Acting Injectable Antipsychotics: A Practical Guide for Prescribers 1 Advantages and disadvantages of long-acting antipsychotics 1.1 Potential advantages 1.2 Potential disadvantages 2 Clinical questions answered 3 Tables summarizing individual agents 3.1Sun, 31 Jan 2016 15:46:43 GMThttps://pharmacologycorner.com/methylphenidate-in-adhd-psychopharmacology/https://pharmacologycorner.com/methylphenidate-in-adhd-psychopharmacology/Dr. Flavio Guzman, from the Psychopharmacology Institute, recently published a new multimedia tutorial on the mechanism of action and formulations of methylphenidate. Here is the outline for the tutorial: 1 Mechanism of action 1.1 The prefrontal cortex and the role of NE and DA in ADHD 1.2 Methylphenidate inhibits the reuptake of NE and DA 2Mon, 22 Jun 2015 14:02:58 GMThttps://pharmacologycorner.com/pharmacotherapy-of-ocd-interview/https://pharmacologycorner.com/pharmacotherapy-of-ocd-interview/First-line treatments of OCD often fail. This means that for some patients, a single SSRI at optimal doses is not enough to achieve remission. In this new Psychopharmacology Institute podcast, Dr. Guzman interviews expert psychiatrist Dr. David Veale on treatment resistant-OCD. It’s interesting to learn about the role of clomipramine in the treatment algorithm. Outline PracticalWed, 29 Apr 2015 01:20:42 GMThttps://pharmacologycorner.com/citalopram-and-escitalopram-compared/https://pharmacologycorner.com/citalopram-and-escitalopram-compared/There are significant differences between these two SSRIs. The FDA warned about the risk of QT prolongation with high doses of citalopram, but not escitalopram. Dosing is different too. To learn more about these similarities and differences check the following video published at the Psychopharmacology Institute website: Citalopram and Escitalopram: A Summary of Key Differences and SimilaritiesThu, 15 May 2014 01:52:35 GMThttps://pharmacologycorner.com/animation-benzodiazepines-diazepam-lorazepam-alprazolam/https://pharmacologycorner.com/animation-benzodiazepines-diazepam-lorazepam-alprazolam/Benzodiazepines and GABA receptors: an animation on their mechanism of action Gamma amino butyric acid (GABA) is an inhibiting neurotransmitter that is present on human brains. As shown in the animation, gamma amino butyric acid promotes opening of a postsynaptic receptor, the GABA-A receptor. This opening leads to a increased conductance to cloride ions, whichTue, 20 Nov 2012 23:10:04 GMThttps://pharmacologycorner.com/videos-opioid-receptors/https://pharmacologycorner.com/videos-opioid-receptors/Click here to view our latest video lecture on opioid receptors. This lecture discusses the following topics: General classification Cellular actions of opioid receptors Anatomical distribution and physiologic effects of mu, delta and kappa receptors Agonists and antagonists ORL-1 receptors Opioid receptorsMon, 10 Oct 2011 23:33:24 GMThttps://pharmacologycorner.com/side-effects-of-ssris/https://pharmacologycorner.com/side-effects-of-ssris/The following video is a short overview on the pharmacological basis of SSRIs side effects. Outline: Facts about SSRIs adverse effects. Gastrointestinal adverse effects. 5-HT3 and 5-HT4 receptors in the GI tract. 5-HT3 receptors in the brainstem and hypothalamus. CNS adverse effects. 5-HT2A receptor stimulation at the basal ganglia. 5-HT2A and 2C receptors are hypotheticallyFri, 20 May 2011 00:08:32 GMThttps://pharmacologycorner.com/therapeutic-index/https://pharmacologycorner.com/therapeutic-index/Therapeutic index explained through graphs. List of narrow therapeutic index drugsWed, 26 Jan 2011 23:46:31 GMThttps://pharmacologycorner.com/glutamate-receptors/https://pharmacologycorner.com/glutamate-receptors/Overview of ionotropic (NMDA, AMPA, Kainate) and metabotropic glutamate receptors (mGluR).Sun, 09 Jan 2011 14:42:58 GMThttps://pharmacologycorner.com/heparin-ppt/https://pharmacologycorner.com/heparin-ppt/PPT discussing chemistry, mechanism of action, classification,pharmacokinetics and clinical uses of heparin.Sun, 19 Dec 2010 14:42:19 GMThttps://pharmacologycorner.com/warfarin-powerpoint-presentation/https://pharmacologycorner.com/warfarin-powerpoint-presentation/PPT on Warfarin pharmacotherapy. Discusses mechanism of action, dosing and target INRs, drug and food interactions, and patient counseling.Sat, 18 Dec 2010 22:49:02 GMThttps://pharmacologycorner.com/alpha-receptors-1-2/https://pharmacologycorner.com/alpha-receptors-1-2/Alpha adrenergic receptors location and effects highlighted in pharmacology charts.Mon, 22 Nov 2010 15:27:22 GMThttps://pharmacologycorner.com/fda-video-tramadol-suicide-ris/https://pharmacologycorner.com/fda-video-tramadol-suicide-ris/FDA video: tramadol and suicide riskMon, 25 Oct 2010 01:58:58 GMThttps://pharmacologycorner.com/ema-use-modafinil-only-for-narcolepsy/https://pharmacologycorner.com/ema-use-modafinil-only-for-narcolepsy/The European Medicines Agency recommended restricting the use of modafinil for narcolepsy only. “The European Medicines Agency has recommended restricting the use of modafinil-containing medicines. The medicine should only be used to treat sleepiness associated with narcolepsy. Doctors and patients should no longer use the medicine for the treatment of idiopathic hypersomnia, excessive sleepiness associated withFri, 22 Oct 2010 02:35:48 GMThttps://pharmacologycorner.com/caution-on-olanzapine-in-adolescents/https://pharmacologycorner.com/caution-on-olanzapine-in-adolescents/Caution on olanzapine in adolescentsFri, 22 Oct 2010 02:13:42 GMThttps://pharmacologycorner.com/propylthiouracil-hepatotoxicity/https://pharmacologycorner.com/propylthiouracil-hepatotoxicity/FDA video about the risks of hepatotoxicity with propylthiouracil.Fri, 22 Oct 2010 02:01:46 GMThttps://pharmacologycorner.com/coagulation-cascade/https://pharmacologycorner.com/coagulation-cascade/Coagulation cascade: several resources (videos, animations and tutorials) depicting coagulation factors and pathways.Wed, 20 Oct 2010 21:49:47 GMThttps://pharmacologycorner.com/ppi-clopidogrel-plavix-interaction/https://pharmacologycorner.com/ppi-clopidogrel-plavix-interaction/Clopidogrel (Plavix) and PPIs resource center: updates on the possible interaction between omeprazole and clopidogrel.Fri, 15 Oct 2010 01:19:26 GMThttps://pharmacologycorner.com/acetylcholine-receptors-muscarinic-and-nicotinic/https://pharmacologycorner.com/acetylcholine-receptors-muscarinic-and-nicotinic/Overview on acetylcholine receptors pharmacology: differences between muscarinic and nicotinic receptors, classification, location, acetylcholine receptors and ANS.Sun, 13 Jun 2010 14:51:37 GMThttps://pharmacologycorner.com/animation-showing-the-jak-stat-signalling-pathway-mechanism/https://pharmacologycorner.com/animation-showing-the-jak-stat-signalling-pathway-mechanism/The Jak-Stat pathway has recently attracted researchers’ attention. This has been motivated by the fact that this pathway is a potential target of future agents for the treatment of myeloproliferative disorders such as: polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. The animation below depicts the Jak-Stat signalling pathway mechanism: As mentioned above, thereSat, 12 Jun 2010 21:12:39 GMThttps://pharmacologycorner.com/thrombolytic-agents-mechanism-of-action-indications-contraindications-and-side-effects/https://pharmacologycorner.com/thrombolytic-agents-mechanism-of-action-indications-contraindications-and-side-effects/Thrombolytic agents are used to lyse already formed blood clots in clinical settings where ischemia may be fatal ( acute mycardial infarction, pulmonary embolism, ischemic stroke, and arterial thrombosis). Very precise indications rule the use of these drugs, which are not free from serious side effects ( bleeding). Outline: Mechanism of action of thrombolytic therapyMon, 10 May 2010 07:05:23 GMThttps://pharmacologycorner.com/pharmacology-elderly-pharmacokinetics-polypharmacy-pp/https://pharmacologycorner.com/pharmacology-elderly-pharmacokinetics-polypharmacy-pp/Collection of different PowerPoint presentations on pharmacological concepts relevant to drug therapy in the geriatric population.Sun, 09 May 2010 03:11:10 GMThttps://pharmacologycorner.com/differences-between-tricyclic-antidepressants-and-selective-serotonin-norepinephrine-reuptake-inhibitors-mechanism-of-action/https://pharmacologycorner.com/differences-between-tricyclic-antidepressants-and-selective-serotonin-norepinephrine-reuptake-inhibitors-mechanism-of-action/Images, mindmaps and tables integration of both TCAs and SNRIs MOA. Muscarinic, histaminic and alpha 1 receptors blockade determines TCAsWed, 28 Apr 2010 21:51:41 GMThttps://pharmacologycorner.com/video-on-aspirin-pharmacokinetics-the-role-of-the-ion-trapping-phenomenon/https://pharmacologycorner.com/video-on-aspirin-pharmacokinetics-the-role-of-the-ion-trapping-phenomenon/Pharmacology video animation on aspirin (ASA) pharmacokinetics. It depicts how pH influences the gastric absorption of aspirin.Mon, 19 Apr 2010 16:40:04 GMT