PowerPoint slides on pharmacodynamics: dose-effect relationship and related concepts

Dr. Edwin Jackson, from the ASPET Division of Cardiovascular Pharmacology, prepared the following PowerPoint lecture on pharmacodynamics, mainly about the dose-effect relationship. The approach is very interesting since its quite clear and simple, but still accurate and thorough.

  • Dose-effect relationships
  • What determines the dose-effect relationship?
  • What is the relationship between [drug] and [drug receptor]?
  • What is the concentration-effect relationship?
  • EC50
  • Spare receptors
  • Potency
  • Full agonist
  • Partial agonist
  • Surmountable antagonist
  • What is the effect of blocking drugs on concentration-response curves?
  • Characteristics of insurmountable antagonists
  • What is a quantal concentration or dose response curve?

Download PPT file

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