Video: Side effects of SSRIs

The following video is a short overview on the pharmacological basis of SSRIs side effects.


  • Facts about SSRIs adverse effects.
  • Gastrointestinal adverse effects.
      5-HT3 and 5-HT4 receptors in the GI tract.
      5-HT3 receptors in the brainstem and hypothalamus.
  • CNS adverse effects.
      5-HT2A receptor stimulation at the basal ganglia.
      5-HT2A and 2C receptors are hypothetically involved in agitation, anxiety and panic attacks.
  • Sexual dysfunction

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