Tag Archive: atrial fibrillation

Animation showing digoxin mechanism of action. Effects at molecular, tissue and system levels

Mechanism of action of digoxin (Lanoxin) reviewed: animation and excerpts of a pharmacology textbook on the pharmacological effects of this cardiac glycoside for heart failure.

More evidence that bisphosphonates do not increase the risk of atrial fibrillation (AF) or flutter

Bisphosphonates don’t increase the risk of atrial fibrillation, according to the study Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety, published in PLoS One on March 2009. The authors used a self-control case series analysis to study nearly 400,000 women from the UK General Practice Research Database. They…

Atrial fibrillation and bisphosphonates: FDA Medwatch update

FDA issued an update to the Agency’s review of safety data regarding the potential increased risk of atrial fibrillation in patients treated with a bisphosphonate drug. Bisphosphonates marketed as Alendronate (Fosamax, Fosamax Plus D) Etidronate (Didronel) Ibandronate (Boniva) Pamidronate (Aredia) Risedronate (Actonel, Actonel W/Calcium) Tiludronate (Skelid) Zoledronic acid (Reclast, Zometa) Bisphosphonates are a class of…

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