Video: Side effects of SSRIs

· Antidepressants

The following video is a short overview on the pharmacological basis of SSRIs side effects.

Outline:

  • Facts about SSRIs adverse effects.

  • Gastrointestinal adverse effects.

    5-HT3 and 5-HT4 receptors in the GI tract.

    5-HT3 receptors in the brainstem and hypothalamus.

  • CNS adverse effects.

    5-HT2A receptor stimulation at the basal ganglia.

    5-HT2A and 2C receptors are hypothetically involved in agitation, anxiety and panic attacks.

  • Sexual dysfunction