Critical care

Articles filed under Critical care.

• Pharmacokinetics in critical care: PowerPoint presentation

  January 6, 2010

  This presentation entitled “Applied Pharmacokinetics in the Adult Critically Ill” is oriented to show pharmacokinetics concepts that are relevant to the ICU. Some of them are: First pass metabolism Patients in whom oral administration should be avoided P-glycoprotein (P-gp) Relevance of drug distribution in compartments Context specific half life Cytochrome 450 Pharmacogenetics Pharmacotherapy in critical

• PowerPoint on neuromuscular blockers pharmacology: mechanism of action, classification, uses, interactions and more

  March 25, 2009

  Neuromuscular blockers: mechanism of action, duration,adverse effects, interactions, cla ssification.By the Dpt. of Pharmacology. Univ. of Beirut

• Xigris (Drotrecogin alfa activated): concerns of serious bleeding and increased death trigger FDA safety review

  February 4, 2009

  On February 4th, 2009 the FDA announced an ongoing safety review of Xigris (Drotrecogin alfa [activated]). An introduction from Wikipedia: Drotrecogin alfa (activated) (Xigris, marketed by Eli Lilly and Company) is a recombinant form of human activated protein C ( rhAPC) that has anti-thrombotic, anti-inflammatory, and profibrinolytic properties. Drotrecogin alpha (activated) belongs to the class