Pharmacokinetics
Articles filed under Pharmacokinetics.
Pharmacokinetics. Compartment(s) definition
The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Compartment(s): The space or spaces in the body, which a drug appears to occupy after it has been absorbed. Pharmacokinetic compartments are mathematical constructs and need not correspond to the fluid volumes of the
Pharmacokinetics. First order kinetics definition and animation.
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. First Order Kinetics: According to the law of mass action, the velocity of a chemical reaction is proportional to the product of the active masses (concentrations) of the reactants.
Pharmacokinetics. A definition of clearance (renal and non renal)
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Clearance: The clearance of a chemical is the volume of body fluid from which the chemical is, apparently, completely removed by biotransformation and/or excretion, per unit time. In fact, the chemical is only partially
Pharmacokinetics topics. What is a generic drug?
This generic drugs definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine . Generic Drugs: Drug formulations of identical composition with respect to the active ingredient, i.e., drugs that meet current official standards of identity, purity, and quality of active ingredient. Drug dosage forms considered as
Alpha 1 adrenergic receptors antagonists (blockers): mechanism of action animation
Additional information about alpha 1 blocking drugs. Source: Bertram G. Katzung, Basic & Clinical Pharmacology (Mc Graw-Hill Medical, 2007) ” Phentolamine, an imidazoline derivative, is a potent competitive antagonist at both alpha 1 and alpha 2 receptors . Phentolamine causes a reduction in peripheral resistance through blockade of alpha 1 receptors and possibly alpha 2
Pharmacokinetics. What is clearance -volume/unit time- (Cl, Clx)?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Cl, Clx: Clearance – in volume/unit time – of a drug or chemical from a body fluid, usually plasma or blood, by specified route(s) and mechanism(s) of elimination, as indicated by a subscript, e.g.,
Pharmacokinetics. What is steady state concentration (Css)?
Pharmacokinetics. Definition of the term steady state in clinical pharmacology.
Pharmacokinetics. What are Cmax and Cmin?
A definition of Cmax and Cmin in clinical pharmacokinetics.
Pharmacokinetics. What is biotranslocation?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine . Biotranslocation: The movement of chemicals (drugs) into, through, and out of biological organisms or their parts. In studying biotranslocation one is concerned with the identification and description of such movement, elucidation of the
Pharmacokinetics. What is biotransformation?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine . Biotransformation: Chemical alteration of an agent (drug) that occurs by virtue of the sojourn of the agent in a biological system. Spontaneous decay of radium would not be considered a biotransformation even if
Myths and facts about generic drugs: FDA presentation
Source: FDA Consumer Education: Generic Drugs
Pharmacodynamics and pharmacokinetics. What is biopharmaceutics?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine . Biopharmaceutics: The science and study of the ways in which the pharmaceutical formulation of administered agents can influence their pharmacodynamic and pharmacokinetic behavior. Differences in pharmaceutical properties can cause substantial differences in the
Pharmacokinetics. What is bioavailability?
Definition of bioavailability in pharmacokinetics.
Pharmacokinetics. What is the area under the curve (AUC)?
Area under the curve in pharmacokinetics: its use in estimating biovailability of drugs.