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Pharmacokinetics study aid: charts, equations and definitions
Study aids by the Department of Pharmacology at University of Utah. Clearance, Volume of distribution, loading dose, maintenance dose.
Vorinostat MSD for cutaneous T-cell lymphoma. MSD withdraws marketing application
Excerpts from the EMEA press release (dated 17th February) on the withdrawal of the marketing application for Vorinostat MSD: The European Medicines Agency (EMEA) has been formally notified by Merck Sharp & Dohme Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Vorinostat MSD (vorinostat), 100 mg hard
What is medical ghostwriting ? Answers to a relevant issue in medical ethics
Article on medical ghostwriting. Definition, links to medical journals on the topic and a video interview.
PowerPoint presentation on cardiovascular pharmacology: calcium channel blockers
This presentation on calcium channel blockers was created by Dr. Nancy Rusch, an expert in the field. It was published on the ASPET Cardiovascular Division website. Calcium channel blockers ppt outline: Introduction (Classification: Phenylalkylamines, Benzothiazepines, 1,4-Dihydropyridines) CCB binding sites Heterogeneity of action Cardiac & hemodynamic differentiation Pharmacokinetics Adverse effects Contraindications Summary Download PPT: Calcium Channel
Barbiturates review: a video lecture
Video lecture. Great study aid to review barbiturates for your pharmacology test. Thiopental, Phenobarbital, Methohexital and Pentobarbital.
Anticonvulsants MCQS for USMLE
Pharmacology questions on anticonvulsants. USMLE style MCQs for pre- test review. Developed by UMKC School of Medicine.
PowerPoint slides on pharmacodynamics: dose-effect relationship and related concepts
Dr. Edwin Jackson, from the ASPET Division of Cardiovascular Pharmacology, prepared the following PowerPoint lecture on pharmacodynamics, mainly about the dose-effect relationship. The approach is very interesting since its quite clear and simple, but still accurate and thorough. Dose-effect relationships What determines the dose-effect relationship? What is the relationship between [drug] and [drug receptor]? What
2009 updated guideline: “Use of chronic opioid therapy in chronic noncancer pain”. Download full text
2009 version of “Guidelines on the use of opioids in treating chronic noncancer pain”. Published in The Journal of Pain. Download free full text
Flash cards on musculoskeletal system drugs: NSAIDS, DMARDS, and anti-gout agents
Free download University of Utah flash cards : Non-steroidal anti-inflammatory drugs (NSAIDS, NAIDs),Drugs for the treatment of rheumathoid arthritis: DMARDs
Disease mongering, direct to consumer advertising and the case of the fake drug Havidol
Disease mongering: a fake drug (Havidol) raises awareness about direct to consumer advertising. Link to a collection of related articles.
Animation on the mechanism of action of GnRH agonists and antagonists in the treatment of prostate cancer
The video animations below depict the mechanism of action of GnRH agonists and antagonists in the treatment of prostate cancer. The three movies will start playing at the same time, you can right-click on each of them and deselect “play” in case you want to stop any of them. This excerpt from the Wikipedia article
Free download: pharmacology flash cards. Antibiotics, antivirals, antiretrovirals and antitubercular drugs
The Department of Pharmacology of the University of Utah has developed some study aids available at their website. Below is the summary of the file on antibiotics and related drugs, and the link to the original file. Antibacterial Drugs Sulfonamides: Sulfisoxazole (Gantrisin), Sulfamethoxazole (Gantanol), Sulfadiazine, Sulfasalazine (Azulfidine), Sulfacetamide sodium (Sulamyd Sodium) Trimethoprim-Sulfamethoxazole (Bactrim, Septra) Chloramphenicol
FDA approves ATryn (recombinant human antithrombin) for the treatment of hereditary antithrombin deficiency
The FDA issued a press release (February 6th, 2009) announcing the approval of the first biological product produced by genetically engineered animals: recombinant human antithrombin. Some excerpts from the press release: The U.S. Food and Drug Administration today issued its first approval for a biological product produced by genetically engineered (GE) animals. The approval is
PowerPoint review: levocetirizine (Xyzal), a third generation antihistamine
This presentation reviews some aspects of the third generation antihistamine Levocetirizine (Xyzal), the active enantiomer of cetirizine (second generation). What do you think? Is Levocetirizine worth it or not? Personally, I don’t see many advantages over other histamine blockers considering pricing factors. Technorati : , Xyzal, levocetirizine, third generation antihistamine
Evidence based medicine and how to critically read papers. Resources to develop an essential skill
It is essential for us, health proessionals , to learn how to critically interpret scientific information. Many times we will read articles that are absolutely irrelevant, or papers that are markedly biased trying to sell us products (new drugs, medical devices). It is our duty to know how to discern the evidence that should guide