Important update on safety information of botulinum toxin type A (Botox)
This is an excerpt of the safety information page about Botox (botulinum toxin type A) posted on the Health Canada website. It warns health professionals about the potential risk of serious adverse effects of muscle weakness remote to the site of injection.
SMC: Zoledronic acid (Aclasta) not recommended for treatment of osteoporosis in men
This is the advice published by the Scottish Medicines Consortium about the use of zoledronic acid for the treatment of osteoporosis in men. ADVICE: in the absence of a submission from the holder of the marketing authorisation. zoledronic acid 5mg (Aclasta®) is not recommended for use within NHSScotland for the treatment of osteoporosis in men […]
Pharmacodynamics (drug receptor interactions): power point presentation
This document has been uploaded to Scribd by Dr. Robert L. Copeland, Pharmacology Professor at Howard University. It deals with basic principles of pharmacodynamics like: Concept of specific drug receptors, Receptor Types, Ion-channel-linked receptors, G-protein-linked receptors, Enzyme-linked receptors, Intracellular receptors, Log Dose-Response Curve, Agonists (or Full Agonists), additivity and sinergism. You can download the power […]
USMLE-like pharmacology quiz. Part 4: pharmacodynamics
The following are multiple choice questions in a style similar to those included in the USMLE step 1. The main topic here is: pharmacodynamics. This quiz has been uploaded to Scribd by medical student James Lamberg. The correct answers can be found in link at the end of this post. Note: the words underlined don’t […]
USMLE-like pharmacology quiz. Part 3: pharmacokinetics (drug metabolism)
The following are multiple choice questions in a style similar to those included in the USMLE step 1. The main topic here is: pharmacokinetics (drug metabolism). This quiz has been uploaded to Scribd by medical student James Lamberg. The correct answers can be found in link at the end of this post. Note: the words […]
USMLE-like pharmacology quiz. Part 2: pharmacokinetics (drug movement and absorption)
The following are multiple choice questions in a style similar to those included in the USMLE step 1. The main topic here is: pharmacokinetics (drug movement and absorption). This quiz has been uploaded to Scribd by medical student James Lamberg. The correct answers can be found in link at the end of this post. Note: […]
USMLE-like pharmacology quiz. Part 1: general principles
The following are multiple choice questions in a style similar to those included in the USMLE step 1. The main topic here is basic principles of pharmacology. This quiz has been uploaded to Scribd by medical student James Lamberg. The answers can be found in link at the end of this post. Note: the words […]
Aliskiren (Rasilez) for essential hypertension: not recommended by the NHS Scotland
The Scottish Medicines Consortium issued on 5th December 2008 an advice on aliskiren (Rasilez, Tekturna in the US): Aliskiren (Rasilez) is not recommended for use within NHS Scotland for the treatment of essential hypertension. Aliskiren has shown comparable efficacy to other antihypertensive agents in terms of blood pressure reduction, though its effects on mortality and […]
Loading dose definition
Loading dose definition and uses in clinical therapeutics.
Inferferons: definition and mechanism of action explained in a flash animation
What are interferons? From Wikipedia: Interferons (IFNs) are natural proteins produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, parasites and tumor cells. Interferons belong to the large class of glycoproteins known as cytokines. Interferons are produced by a wide variety of cells […]
Definition of half life of drugs
What is half life in pharmacokinetics? A pharmacological definition and an analysis to its formula.
Rivaroxaban (Xarelto) for the prevention of venous thromboembolism (VTE): SMC review
The Scottish Medicines Consortium issued on 7th November, 2008 an advice on rivaroxaban (Xarelto): ADVICE: following a full submissionrivaroxaban (Xarelto®) is accepted for use within NHS Scotland for the prevention of venous thromboembolism (VTE) in adult patients undergoing elective hip or knee replacement surgery.In three large phase III studies in patients undergoing either total knee […]
Antipsychotics would increase mortality in patients with Alzheimer’s disease
Via Physician’s First Watch: Patients with Alzheimer Disease on Antipsychotics Show Increased Mortality Patients with Alzheimer disease who take antipsychotic drugs may be at increased long-term risk for death, according to a study published online in Lancet Neurology.
Natalizumab (Tysabri) for multiple sclerosis: AAN guideline and recommendations
The American Academy of Neurology (AAN) published via the National Guideline Clearinghouse a set of recommendations for the use of the monoclonal antibody Natalizumab (Tysabri) for multiple sclerosis: MAJOR RECOMMENDATIONS Definitions of the strength of the recommendations (A, B, C, U) and classification of the evidence (Class I through Class IV) are provided at the […]