The following video is a short overview on the pharmacological basis of SSRIs side effects.
Outline:
- Facts about SSRIs adverse effects.
- Gastrointestinal adverse effects.
- 5-HT3 and 5-HT4 receptors in the GI tract.
- 5-HT3 receptors in the brainstem and hypothalamus.
- CNS adverse effects.
- 5-HT2A receptor stimulation at the basal ganglia.
- 5-HT2A and 2C receptors are hypothetically involved in agitation, anxiety and panic attacks.
- Sexual dysfunction