Thrombolytic agents: mechanism of action, indications, contraindications and side effects
Thrombolytic agents are used to lyse already formed blood clots in clinical settings where ischemia may be fatal ( acute mycardial infarction, pulmonary embolism, ischemic stroke, and arterial thrombosis). Very precise indications rule the use of these drugs, which are not free from serious side effects ( bleeding). Outline: Mechanism of action of thrombolytic therapy […]
Golimumab (Simponi) side effects: risk of serious fungal infections
Centocor Ortho Biotech and FDA reminded prescribers of the risk of serious fungal infections associated with TNF-α blockers, this includes the newer Simponi (golimumab).
FDA video on erlotinib (Tarceva) adverse effects
FDA video warning on gastrointestinal dermatologic and ophthalmic side effects of erlotinib (Tarceva).
Propylthiouracil (PTU) side effects: FDA warned about risk of hepatotoxicity
The FDA warned prescribers about the risk of serious liver injury associated with the use of the anti-thyroid drug propylthiouracil (PTU). FDA’s warning highlights: There is an increased risk of liver injury with propylthiouracil (PTU) when compared to methimazole. Monitor for symptoms and signs of liver injury when propylthiouracil is chosen as anti-thyroid therapy. This […]
Zolpidem, zoplicone and zaleplon (z-drugs) side effects profile: Australian Prescriber press release
Hypnotic hazards and effects of z-drugs immeasurable “It is difficult to know the extent of use and adverse effects of zolpidem and other z-drugs (zopiclone and zaleplon) because they have never been listed on the Australian Pharmaceutical Benefits Scheme, senior Sleep Disorders Physician Dr Les Olson writes in the latest edition of Australian Prescriber.