Atypical antipsychotics and sudden cardiac death: medical media coverage

This is a compilation of the media impact of the recent paper published in the NEJM: Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death. Atypical antipsychotics (Second generation antipsychotics) include: Clozapine (Clozaril),Olanzapine (Zyprexa),Risperidone (Risperdal), Quetiapine (Seroquel), Ziprasidone (Geodon), Amisulpride (Solian), Paliperidone (Invega) Physician’s First Watch Antipsychotics Increase Risks for Sudden Cardiac Death

Quetiapine extended release tablets (Seroquel XR): efficacy, tolerability and adherence.

Information about quetiapine extended release tablets, from the National Prescribing Service RADAR “There is no evidence that extended-release tablets improve efficacy, tolerability or adherence Once-daily dosing with quetiapine extended-release tablets is equivalent to twice-daily dosing with quetiapine immediate-release tablets, e.g. quetiapine extended release 600 mg once daily is equivalent to quetiapine immediate release 300 mg […]

Paliperidone (Invega) manufacturer withdraws application for its use in bipolar disorder

Reproduction of EMEA’s press release about the Janssen-Cilag International¬† application withdrawal for an extension of indication for Invega (paliperidone): PRESS RELEASE Janssen-Cilag International N.V. withdraws its application for an extension of indication for Invega (paliperidone) The European Medicines Agency (EMEA) has been formally notified by Janssen-Cilag International N.V. of its decision to withdraw its application […]

Antipsychotics for acute and chronic pain: a systematic review

Summary Analgesic effects of antipsychotics in acute and chronic painful states Antipsychotics are used in different chronic pain states (e.g. chronic headache, fibromyalgia and diabetic neuropathia). With atypical antipsychotics a new class of antipsychotics is available, with lesser extrapyramidal side effects and additional benefits. The review authors assessed the analgesic efficacy and adverse effects of […]