SMC recommendations for doripenem : second or third line treatment of intra-abdominal infections
The Scottish Medicines Consortium issued an advice on the current indications for doripenem (Doribax): Doripenem (Doribax) is accepted for restricted use within NHS Scotland for the treatment of complicated intra-abdominal infections in adults. In patients with complicated intra-abdominal infection, doripenem is associated with clinical cure rates non-inferior to those of another carbapenem. Doripenem should be […]
Beta lactams antibiotics (penicillins and cephalosporins) mechanism of action: videos and animations
Mechanism of action of the beta lactam antibiotics (penicillins and cephalosporins) The beta-lactam antibiotics can kill susceptible bacteria. Although knowledge of the mechanism of this action is incomplete, numerous researchers have supplied information that allows understanding of the basic phenomenon (seeGhuysen, 1991; Bayles, 2000). The cell walls of bacteria are essential for their normal growth […]