Serotonin 5-HT3-receptor antagonists: pharmacokinetics, MOA, indications and adverse effects

This posts overviews the general characteristics, pharmacokinetics, mechanism of action, dosing, indications and adverse effects profile of serotonin 5-HT3-receptor antagonists. These drugs are being increasingly used for the prevention of chemotherapy induced nausea and vomiting as well as antiemetic prophylaxis of post-operative and post-radiation nausea and vomiting.

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