Animation: NRTIs mechanism of action

Nucleoside analog reverse transcriptase inhibitors (NRTIs) are nucleoside analogues that act as competitive inhibitors of HIV-1 reverse transcriptase. As shown in the animation, these drugs compete with nucleoside triphosphates for access to reverse transcriptase. All NRTIs lack a 3-hydroxyl group; thus, their incorporation into a growing DNA chain results in its termination. They require intracytoplasmic […]

Antiretrovirals drugs: video review for nurses (NCLEX)

This video review covers the medications used for the treatment of HIV infection. The target audience of the review is nursing students and nurses, it covers mainly adverse effects of the different drug classes. More on nursing pharmacology Technorati : HIV, NCLEX, NRTIs,  NNRTI, Nurses & nursing students

Etravirine (Intelence) review from Health Canada

Information about: etravirine (Intelence) for the treatment of HIV-1 infection in treatment-experienced adult patients who have failed prior therapy and have HIV-1 strains resistant to multiple antiretroviral agents, including NNRTIs. From Health Canada. On March 27, 2008, Health Canada issued a Notice of Compliance to Janssen-Ortho Inc. for the drug product Intelence.

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