Methylnaltrexone (Relistor): clinical updates from two independent sources

Methylnaltrexone (Relistor) is a peripherally-acting μ-opioid antagonist used for the treatment of opioid induced constipation. Two independent organizations have recently published updated clinical information on this drug: Australian Prescriber. New drugs: Methylnaltrexone Health Canada. Summary Basis of Decision (SBD) RELISTOR The Scottish Medicines Consortium also reviewed Relistor in January 2009.