Pharmacodynamics topics. What is intrinsic efficacy (intrinsic activity)?
A definition of the pharmacodynamic concept of intrinsic efficacy (intrinsic activity).
Pharmacodynamics animation: full agonists, partial agonists, inverse agonists, competitive antagonists and irreversible antagonists.
First, some pharmacodynamic definitions related to the animation: Full Agonists: Compounds that are able to elicit a maximal response following receptor occupation and activation. Partial Agonists: Compounds that can activate receptors but are unable to elicit the maximal response of the receptor system. Inverse agonist: an agent which binds to the same receptor binding-site as […]
Pharmacodynamics. What is a bioassay or biological assay?
Pharmacodynamics definition of biological assay or bioassay.
Pharmacodynamics. Antagonism: definition, types (chemical, physiological, pharmacological)
Definitions of different types of antagonism: chemical, pharmacological and physiological.
Pharmacodynamics topics. What is affinity?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Affinity: The equilibrium constant of the reversible reaction of a drug with a receptor to form a drug-receptor complex; the reciprocal of the dissociation constant of a drug-receptor complex. Under the most general conditions, […]