Pharmacodynamics animation: full agonists, partial agonists, inverse agonists, competitive antagonists and irreversible antagonists.

First, some pharmacodynamic definitions related to the animation: Full Agonists: Compounds that are able to elicit a maximal response following receptor occupation and activation. Partial Agonists: Compounds that can activate receptors but are unable to elicit the maximal response of the receptor system. Inverse agonist: an agent which binds to the same receptor binding-site as […]

Pharmacodynamics topics. What is affinity?

The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Affinity: The equilibrium constant of the reversible reaction of a drug with a receptor to form a drug-receptor complex; the reciprocal of the dissociation constant of a drug-receptor complex. Under the most general conditions, […]

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