Geriatric pharmacology: pharmacokinetics, polypharmacy and related topics
Collection of different PowerPoint presentations on pharmacological concepts relevant to drug therapy in the geriatric population.
Pharmacokinetics in critical care: PowerPoint presentation
This presentation entitled “Applied Pharmacokinetics in the Adult Critically Ill” is oriented to show pharmacokinetics concepts that are relevant to the ICU. Some of them are: First pass metabolism Patients in whom oral administration should be avoided P-glycoprotein (P-gp) Relevance of drug distribution in compartments Context specific half life Cytochrome 450 Pharmacogenetics Pharmacotherapy in critical […]
Cochrane review podcast: Commercial spacers as effective as home-made?
Spacers in combination with metered-dose inhalers for delivery of bronchodilator drugs have proved to be effective. However, in some low income areas ( mainly in developing countries) it may not be something affordable or accesible to patients. As a response to this issue, home-made spacers (tipically with plastic bottles) have been widely used. In this Cochane […]
Pharmacokinetics: Intramuscular injection administration. Video animation
Recommended pharmacokinetics reading Pocket Guide: Pharmacokinetics Made Easy (2009) Basic Clinical Pharmacokinetics (2009) Concepts in Clinical Pharmacokinetics (2010) Clinical Pharmacokinetics, 4th Edition (2008)
Definition of half life of drugs
What is half life in pharmacokinetics? A pharmacological definition and an analysis to its formula.
Absorption rate constant (ka) definition
Absorption rate constant (ka), a pharmacokinetic definition.
Pharmacology mnemonic: drugs that induce enzymatic metabolism
Metabolism enzyme inducers “Randy’s Black Car Goes Putt Putt and Smokes “: Rifampin Barbiturates Carbamazepine Grisoefulvin Phenytoin Phenobarb Smoking cigarettes Thanks to MedExcel
Pharmacology glossary. Dose duration curve definition
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Dose-Duration Curve: The curve describing the relationship between dose (as the independent variable) and duration of drug effect (as the dependent variable, T). The slope of the curve is always positive, in contrast to
Pharmacokinetics video. Absorption of drugs by oral route
More information about the oral route of drug administration: Oral (p.o.) Ingestion a. Convenient route for administration of solid as well as liquid formulations.
Pharmacokinetics. Compartment(s) definition
The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Compartment(s): The space or spaces in the body, which a drug appears to occupy after it has been absorbed. Pharmacokinetic compartments are mathematical constructs and need not correspond to the fluid volumes of the […]
Pharmacokinetics. First order kinetics definition and animation.
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. First Order Kinetics: According to the law of mass action, the velocity of a chemical reaction is proportional to the product of the active masses (concentrations) of the reactants.
Pharmacokinetics. A definition of clearance (renal and non renal)
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Clearance: The clearance of a chemical is the volume of body fluid from which the chemical is, apparently, completely removed by biotransformation and/or excretion, per unit time. In fact, the chemical is only partially […]
Pharmacokinetics. What is clearance -volume/unit time- (Cl, Clx)?
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Cl, Clx: Clearance – in volume/unit time – of a drug or chemical from a body fluid, usually plasma or blood, by specified route(s) and mechanism(s) of elimination, as indicated by a subscript, e.g., […]
Pharmacokinetics. What is steady state concentration (Css)?
Pharmacokinetics. Definition of the term steady state in clinical pharmacology.