FDA updated information about a safety review of Ezetimibe/Simvastatin (Vytorin), Ezetimibe (Zetia), and Simvastatin (Zocor)
FDA updated yesterday ( January 8, 2009) information related to their review of the ENHANCE trial: On January 25, 2008, FDA announced that it would be reviewing data from the ENHANCE trial (Effect of Combination Ezetimibe and High-Dose Simvastatin vs. Simvastatin Alone on the Atherosclerotic Process in Patients with Heterozygous Familial Hypercholesterolemia). (http://www.fda.gov/cder/drug/early_comm/ezetimibe_simvastatin.htm). Preliminary results from this […]
Pharmacology mnemonic. HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions
Pharmacology mnemonic about: HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions HMG CoA: Side effects: H epatotoxicity M yositis [aka rhabdomyolysis] _ Contraindications: G irl during pregnancy/G rowing children _ Interactions: C oumarin/ C yclosporine Also, check a related animation on their mechanism of action. Thanks to MedExcel