Animation: insulin secretion and sulfonylureas mechanism of action
Animation that depicts how sulfonylureas enhance insulin secretion by binding to specific beta cell receptors. Download available
Sulfonylureas: consensus statement published on Diabetes Care
Below is a transcript of the latest statement (December 2008) published on Diabetes Care about the role of sulfonylureas in the medical management of hyperglycemia in type 2 diabetes. Sulfonylureas. Sulfonylureas lower glycemia by enhancing insulin secretion (see mechanism of action). In terms of efficacy, they appear to be similar to metformin, lowering A1C levels by 1.5 percentage points (26,49). […]