Elimination rate constant (kel) definition
The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. kel: The “elimination rate constant” for a drug eliminated according to the laws of first-order reaction kinetics; the slope of the plot of the logarithm of concentration against time, when natural logarithms, i.e. logarithms […]
Mnemonic to remember which benzodiazepines don’t have hepatic metabolism
Benzodiazepines: ones not metabolized by the liver (safe to use in liver failure) LOT: Lorazepam Oxazepam Temazepam Thanks to MedExcel Remember to check the animation on the mechanism of action of benzodiazepines.
Equivalence definition in pharmacology: three kinds of equivalence
The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Equivalence: In 1969, a federal Task Force on Prescription Drugs recommended that the words “generic equivalents” no longer be used in describing and comparing drug preparations. The Task Force recommended that an appropriate nomenclature […]
Efficacy definition in pharmacodynamics
Pharmacodynamics definition of efficacy.
Potency of a drug. Equipotent drug definition
The following pharmacology definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Equipotent: Equally potent, or equally capable of producing a pharmacologic effect of a specified intensity. The masses of the drugs required to produce this degree of effect may be compared, quantitatively, to
Phenytoin adverse effects mnemonic
Phenytoin: adverse effects PHENYTOIN: P-450 interactions Hirsutism Enlarged gums (Gingival hyperplasia, the most common) Nystagmus Yellow-browning of skin Teratogenicity Osteomalacia Interference with B12 metabolism (hence anemia) Neuropathies: vertigo, ataxia, headache Thanks to MedExcel
Mnemonic for direct sympathomimetic catecholamines
Direct sympathomimetic catecholamines mnemonic DINED: Dopamine Isoproterenol Norepinephrine Epinephrine Dobutamine Thanks to MedExcel
Pharmacodynamics definitions. Receptor desensitization
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Desensitization: A decline in the response to repeated or sustained application of an agonist that is a consequence of changes at the level of the receptor. The copyright of the text is hold by […]
Pharmacology mnemonic. Inhalational anaesthetics
Inhalational anesthetics SHINE: Sevoflurane Halothane Isoflurane Nitrous oxide Enflurane Thanks to MedExcel
Pharmacology mnemonics. Direct sympathomimetic catecholamines
Direct sympathomimetic catecholamines DINED: Dopamine Isoproterenol Norepinephrine Epinephrine Dobutamine Thanks to MedExcel
Pharmacology mnemonic. Anticholinergic side effects
Anticholinergic side effects “Know the ABCD’S of anticholinergic side effects”: Anorexia Blurry vision Constipation/ Confusion Dry Mouth Sedation/ Stasis of urine Thanks to MedExcel
Pharmacodynamics. Ceiling definition
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Ceiling: The maximum biological effect that can be induced in a tissue by a given drug, regardless of how large a dose is administered.
Pharmacology mnemonic. Beta 1 and beta 2 receptor location.
Beta-1 vs Beta-2 receptor location “You have 1 heart and 2 lungs”: Beta-1are therefore primarily on heart Beta-2 primarily on lungs Thanks to Medexcel
Pharmacology mnemonic. Thrombolytic agents
Thrombolytic agents USA: Urokinase Streptokinase Alteplase (tPA) Thanks to MedExcel