Category Archives: Cardiovascular

Warfarin PowerPoint presentation

PPT on Warfarin pharmacotherapy. Discusses mechanism of action, dosing and target INRs, drug and food interactions, and patient counseling.Continue Reading

Alpha receptors

Alpha adrenergic receptors location and effects highlighted in pharmacology charts.Continue Reading

The coagulation cascade

Coagulation cascade: several resources (videos, animations and tutorials) depicting coagulation factors and pathways.Continue Reading

Hypertension management: pharmacotherapy lecture notes (PDF)

Phharmacological management of hypertension: by the Pharmacology OpenCourseWare initiative at Harvard Medical School – MIT.Continue Reading

Calcium channel blockers: classification, mechanism of action and indications

Overview on calcium channel blockers, in this first part we will discuss their classification, mechanism of action as well as clinical indications.Continue Reading

Drug therapy for heart failure: PowerPoint presentations

Both lectures provide an introduction on clinical features of the disease and its physiopathology, later they review the most relevant pharmacological properties of each drug class.Continue Reading

COGENT trial: no clopidogrel-PPIs interaction

According to the results of the COGENT trial, the combination of the antiplatelet clopidogrel and the PPI omeprazole does not produce clinically relevant cardiovascular interactions.Continue Reading

Prasugrel (Effient): mechanism of action, indications and adverse effects

Overview on the mechanism of action, indications, adverse effects profile of prasugrel (Efient in the EU, Effient in the USA). PowerPoint on the TIMI TRITON 38 trial.Continue Reading

PPIs reduce the effectiveness of clopidogrel (Plavix)

Pharmamotion has now a new page containing updates on  clopidogrel – PPI interactions. The latest edition of the monthly newsletter from the Medicines and Healthcare products Regulatory Agency has issued a drug safety advice on the interaction between the antiplatelet drug clopidogrel (Plavix) and PPIs. They conclude that available data supports a clinically significant interactionContinue Reading

ACE inhibitors and angiotensin II receptor blockers should be avoided in pregnancy and during breastfeeding

UK’s MHRA: do not to use ACE inhibitors and angiotensin II receptor antagonists while breastfeeding. Hypertension Journal reviews ACEI toxicity in pregnancy.Continue Reading

Cardiac arrhythmias made easy: a video you’ll never forget

Easy to understand video on cardiac electrophysiology. A cardiology professor acts the main types of cardiac arrhythmias (including atrial fibrillation and flutter).Continue Reading

Animation on coagulation physiology and the mechanism of action of glycoprotein IIb/IIIa antagonists

Animation on coagulation physiology and mechanism of action of Gp IIb/IIIa inhibitors (abciximab, eptifibatide and tirofiban) and other antiplatelet drugs.Continue Reading

Digoxin Mechanism of Action: Animated Tutorial

Mechanism of action of digoxin (Lanoxin) reviewed: animation and excerpts of a pharmacology textbook on the pharmacological effects of this cardiac glycoside for heart failure.Continue Reading

MCQs on cardiovascular pharmacology. Pre-test practice review: vasodilators and inotropes

MCQs on cardiovascular pharmacology: inotropics and vasodilators. For USMLE step 1 review. More MCQs on other pharmacological topics.Continue Reading

Are you a visual learner interested in learning psychopharmacology? Click here to get our videos