Category Archives: Pain drug therapy

An excellent animation on the mechanisms of drug addiction

The Genetic Science Learning Center at University of Utah developed an excellent animation depicting the mechanisms of addiction of most drugs of abuse. They use a cartoon-like approach to show molecular changes in mouse brains.

Watch animation

They approach the following topics related to the neurobiology of drug addiction.

  • Methamphetamine actions on dopamine vesicles.
  • LSD action on serotonin receptors.
  • Heroin effects on opioid receptors .
  • How marijuana interacts with the cannabinoid system and its receptors.
  • Activation of the GABA-A ionotropic receptor by alcohol.
  • Cocaine action on dopamine reuptake.

This blog has a related post that explains nicotine addiction mechanism through a 3-D video animation.

FDA video warning about local anesthetics side effects

Local anesthetics side effects are covered in the March 2009 edition of FDA’s Patient Safety News. The agency’s concern is that after a study published in the the journal Radiology in which the authors suggest the use of topical anesthetics to reduce disconfort during mammography, more and more women will start using them without being…

Updated SIGN clinical guideline: Pain management in adults with cancer

The Scottish Intercollegiate Guidelines Network (SIGN) updated a clinical guideline entitled “Control of pain in adults with cancer”.  An outline of the contents (drug therapy related) in this guideline for the treatment of cancer induced pain include: Principles of pain management: introduction, World Health Organization cancer pain relief programme, using the WHO ladder. Treatment with…

Intravenous and inhalational anesthetics, MCQs for test review

I believe some of the questions ( developed by the UMKC School of Medicine) in this set would be more suitable for an anesthesiologist or anesthesia resident than for a medical student in the pre-clinical years. However, most of them are regular questions from classic pharmacology textbooks. I hope you find them useful. Item Number: correct answer: 2 category: Anesthetics 1. All of the following factors…Continue Reading

Analgesics (opioids, nsaids): MCQs for pharmacology review

These questions have been created by the Department of Pharmacology, UMKC School of Medicine.  The use I suggest is to review your knowledge of the subject for USMLE or other pharma test.   Did you find them useful? Too hard ? Too easy? Use the comment form to comment what did you think of them! Item Number: 1684 correct answer: 5 category: Analgesics 1. A child has ingested an unknown substance and has evidence of respiratory depression.…Continue Reading

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