Animation: NRTIs mechanism of action
Nucleoside analog reverse transcriptase inhibitors (NRTIs) are nucleoside analogues that act as competitive inhibitors of HIV-1 reverse transcriptase. As shown in the animation, these drugs compete with nucleoside triphosphates for access to reverse transcriptase. All NRTIs lack a 3-hydroxyl group; thus, their incorporation into a growing DNA chain results in its termination. They require intracytoplasmic […]
Etravirine (Intelence) for HIV infection: not recommended by the Scottish Medicines Consortium
This is an excerpt from the Scottish Medicines Consortium (SMC) advice on etravirine (Intelence). ADVICE: following a full submission etravirine (Intelence), in combination with a boosted protease inhibitor and other antiretroviral medicinal products, is not recommended for use within NHS Scotland for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in antiretroviral treatment-experienced […]
Antiretrovirals drugs: video review for nurses (NCLEX)
This video review covers the medications used for the treatment of HIV infection. The target audience of the review is nursing students and nurses, it covers mainly adverse effects of the different drug classes. More on nursing pharmacology Technorati : HIV, NCLEX, NRTIs, NNRTI, Nurses & nursing students