Nucleoside analog reverse transcriptase inhibitors (NRTIs) are nucleoside analogues that act as competitive inhibitors of HIV-1 reverse transcriptase. As shown in the animation, these drugs compete with nucleoside triphosphates for access to reverse transcriptase. All NRTIs lack a 3-hydroxyl group; thus, their incorporation into a growing DNA chain results in its termination. They require intracytoplasmic […]
Brief introduction to the general principles of the pharmacology of infections. Though oriented to a general audience, it is a very interesting and accurate presentation on antibiotics and antivirals.
The following images created by the Dept. of Pharmacology at University of Utah are great for reviewing antifungals before a test like USMLE: This table contains the following agents: Trifluridine, Vidarabine, acyclovir, ganciclovir, foscarnet, azt, ddI, ribavirin, amantadine.
This video is targeted to nurses and nursing students, as a pharmacology review previous to the NCLEX exam. It reviews the following drug classes: Antimycobacterial (antitubercular) drugs: isoniazid, pyrazinamide, rifampin, ethambutol Drugs for the treatment of herpesvirus infections: acyclovir famciclovir Drugs for the treatment of influenza:amantadine, rimantadine, zanamivir, oseltamivir Drugs for the treatment of citomegalovirus […]