Zonisamide (Zonegran): FDA warns about risk of metabolic acidosis and issues recommendations
The FDA issued an alert (February 23, 2009) about the risk of metabolic acidosis in patients treated with zonisamide (Zonegran). An excerpt from the alert on this anticonvulsant adverse effect: Following a review of updated clinical data, the FDA has determined that treatment with zonisamide can cause metabolic acidosis in some patients. Zonisamide is indicated […]
Scottish Medicines Consortium accepted Adalimumab (Humira) for adolescents that do not respond to other DMARDs
An excerpt from the Drug Advice issued by the Scottish Medicines Consortium on adalimumab (Humira): adalimumab (Humira) is accepted for restricted use in NHS Scotland, in combination with methotrexate, for the treatment of active polyarticular juvenile idiopathic arthritis in adolescents aged 13-17 years who have an inadequate response to one or more disease-modifying anti-rheumatic drugs […]
PowerPoint presentation: ACE inhibitors, ARBs, and calcium channel blockers
The following pharmacology PowerPoint has been developed by Ed Sheridan, Pharm.D. Outline: ACE inhibitors, Angiotensin II Receptor Blockers (ARBs), and calcium channel blockers •Review the Mechanism of Action •Review Safety •Review Efficacy •Hypertension Download ppt slides: pharmacology of ACEi, ARBs, and Calcium channel blockers. You may also find interesting related PowerPoint presentation on drug therapy […]
EMEA recommends new contraindication for aliskiren (Rasilez): angioedema
According to the EMEA, aliskiren (Rasilez, Tekturna in the USA) should not be prescribed in patients that experienced angioedema after taking the drug. Some excerpts from the EMEA press release dated 19 February, 2009: The European Medicines Agency (EMEA) has recommended adding a contraindication to the Product Information for aliskiren, stating that it must not […]
Endocrine drugs flash cards
Endocrine pharmacology flash cards by Department of Pharmacology at University of Utah.Bisphosphonates,insulins, antidiabetic agents, antithyroid drugs.
USMLE video lecture review on propofol
Video review on chemistry, mechanism of action and pharmacokinetics of propofol (short-acting intravenous sedative agent, used for the induction of general anesthesia). Quite useful when you get tired of studying pharmacology.
Cardiovascular MCQs for pharmacology review. USMLE style questions on antiarrhythmics
Pharmacology questions on antiarrhythmics. USMLE style MCQs for pre- test review. Developed by UMKC School of Medicine.
Efalizumab (Raptiva) for plaque psoriasis. EMEA recommends withdrawal of its marketing authorization, FDA issues public health advisory
Raptiva and progressive multifocal leukoencephalopathy : EMEA recommends withdrawal of marketing authorization and FDA recommends monitoring patients.
Drug development approval process. PowerPoint presentation and CME credit available
Southern Collaboration in Research to Impact Prescription of Therapeutics (SCRIPTS) is a project aimed to”help prescribers enhance their ability to evaluate drug related information to improve their prescribing practices and describe proper prescribing practices to improve quality of patient care”. It is sponsored by University of Alabama at Birmingham. This is the first module concerning […]
USMLE-like questions on antihypertensives
These questions from the UMKC School of Medicine have a different degree of difficulty, but are useful to review pharmacology of hypertension. Antihypertensives Item Number: 11201 correct answer: 4 category: Antihypertensives 1. Gynecomastia, hyperkalemia, and menstrual abnormalities are potential adverse effects associated with: A. amiloride B. captopril C. triamterene D. spironolactone 1. A,B,C 2. A,C […]
Pharmacokinetics study aid: charts, equations and definitions
Study aids by the Department of Pharmacology at University of Utah. Clearance, Volume of distribution, loading dose, maintenance dose.
Vorinostat MSD for cutaneous T-cell lymphoma. MSD withdraws marketing application
Excerpts from the EMEA press release (dated 17th February) on the withdrawal of the marketing application for Vorinostat MSD: The European Medicines Agency (EMEA) has been formally notified by Merck Sharp & Dohme Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Vorinostat MSD (vorinostat), 100 mg hard […]
What is medical ghostwriting ? Answers to a relevant issue in medical ethics
Article on medical ghostwriting. Definition, links to medical journals on the topic and a video interview.
PowerPoint presentation on cardiovascular pharmacology: calcium channel blockers
This presentation on calcium channel blockers was created by Dr. Nancy Rusch, an expert in the field. It was published on the ASPET Cardiovascular Division website. Calcium channel blockers ppt outline: Introduction (Classification: Phenylalkylamines, Benzothiazepines, 1,4-Dihydropyridines) CCB binding sites Heterogeneity of action Cardiac & hemodynamic differentiation Pharmacokinetics Adverse effects Contraindications Summary Download PPT: Calcium Channel […]