The European Medicines Agency recommended restricting the use of modafinil for narcolepsy only. “The European Medicines Agency has recommended restricting the use of modafinil-containing medicines. The medicine should only be used to treat sleepiness associated with narcolepsy. Doctors and patients should no longer use the medicine for the treatment of idiopathic hypersomnia, excessive sleepiness associated with […]
Coagulation cascade: several resources (videos, animations and tutorials) depicting coagulation factors and pathways.
Clopidogrel (Plavix) and PPIs resource center: updates on the possible interaction between omeprazole and clopidogrel.
Overview on acetylcholine receptors pharmacology: differences between muscarinic and nicotinic receptors, classification, location, acetylcholine receptors and ANS.
The Jak-Stat pathway has recently attracted researchers’ attention. This has been motivated by the fact that this pathway is a potential target of future agents for the treatment of myeloproliferative disorders such as: polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. The animation below depicts the Jak-Stat signalling pathway mechanism: As mentioned above, there […]
Thrombolytic agents are used to lyse already formed blood clots in clinical settings where ischemia may be fatal ( acute mycardial infarction, pulmonary embolism, ischemic stroke, and arterial thrombosis). Very precise indications rule the use of these drugs, which are not free from serious side effects ( bleeding). Outline: Mechanism of action of thrombolytic therapy […]
Collection of different PowerPoint presentations on pharmacological concepts relevant to drug therapy in the geriatric population.
Images, mindmaps and tables integration of both TCAs and SNRIs MOA. Muscarinic, histaminic and alpha 1 receptors blockade determines TCAs
Pharmacology video animation on aspirin (ASA) pharmacokinetics. It depicts how pH influences the gastric absorption of aspirin.
Serotonin receptors characteristics, classification and drugs that influence serotonergic transmission. Pharmacology review.
The following set of lectures has been created by Dr. Edwin Jackson and were published in the Division for Cardiovascular Pharmacology, a branch of the American Society for Pharmacology and Experimental Therapeutics (ASPET). Why study autonomic pharmacology? Outline of slides: Parasympathetic Ganglionic Synapse, Parasympathetic Organ Synapse, Sympathetic Ganglionic Synapse, Sympathetic Ganglionic Synapse, How do drugs […]