Pharmacokinetics. First order kinetics definition and animation.
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. First Order Kinetics: According to the law of mass action, the velocity of a chemical reaction is proportional to the product of the active masses (concentrations) of the reactants.
Pharmacology mnemonics. Direct sympathomimetic catecholamines
Direct sympathomimetic catecholamines DINED: Dopamine Isoproterenol Norepinephrine Epinephrine Dobutamine Thanks to MedExcel
Pharmacology mnemonic. Anticholinergic side effects
Anticholinergic side effects “Know the ABCD’S of anticholinergic side effects”: Anorexia Blurry vision Constipation/ Confusion Dry Mouth Sedation/ Stasis of urine Thanks to MedExcel
Pharmacokinetics. A definition of clearance (renal and non renal)
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Clearance: The clearance of a chemical is the volume of body fluid from which the chemical is, apparently, completely removed by biotransformation and/or excretion, per unit time. In fact, the chemical is only partially […]
Pharmacodynamics. Ceiling definition
The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Ceiling: The maximum biological effect that can be induced in a tissue by a given drug, regardless of how large a dose is administered.
EMEA press release: CHMP adopted positive opinion about mifamurtide (Mepact) for the treatment of osteosarcoma
EMEA press release informing the CHMP positive opinion about mifamurtide (Mepact), for the treatment of high grade resectable non metastatic osteosarcoma. COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for MEPACT International Nonproprietary Name (INN): mifamurtide On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive […]
FDA approves imatinib (Gleevec) for a new indication: GIST tumors.
FDA press relase about the approval of imatinib (Gleevec) for the treatment of GIST tumors: FOR IMMEDIATE RELEASE December 19, 2008 FDA Approves Gleevec to Prevent Recurrence of Rare Gastrointestinal Cancer The U.S. Food and Drug Administration today approved Gleevec (imatinib mesylate) for a new indication –
EMEA press release: CHMP positive opinion about degarelix (Firmagon) for prostate cancer
COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for FIRMAGON International Nonproprietary Name (INN): degarelix (as acetate) On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing authorisation for the medicinal product Firmagon, 80 mg and 120 mg, powder and […]
FDA approves plerixafor (Mozobil) for use in multiple myeloma and non Hodgkin’s lymphomas
From the FDA’s newsroom: FDA Approves Drug that Boosts Stem Cell Yield for Bone Marrow Transplants The U.S. Food and Drug Administration today approved Mozobil (plerixafor), a drug that helps increase the number of blood stem cells for bone marrow transplantation in patients with certain forms of blood cancer. Mozobil is intended to be used […]
CHMP positive opinion for lasofoxifene (Fablyn), a new SERM
Press release about the positive opinion of the CHMP for Fablyn (lasofoxifene): COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for FABLYN International Nonproprietary Name (INN): lasofoxifene On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing authorisation for the […]
CHMP positive opinion for new indication of miglustat (Zavesca)
Press release from the CHMP about a new indication for Zavesca (miglustat): COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE POST-AUTHORISATION SUMMARY OF POSITIVE OPINION for ZAVESCA International Nonproprietary Name (INN): miglustat On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion to recommend the variation to the terms […]
EMEA positive opinion for prasugrel (Efient)
Press release about the positive opinion of the CHMP for the antiplatelet agent Efient (prasugrel): COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for EFIENT International Nonproprietary Name (INN): prasugrel On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing […]
EMEA press release: CHMP adopted a positive opinion about japanese encephalitis vaccine (Ixiaro)
COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for IXIARO Common Name: Japanese Encephalitis vaccine, inactivated, adsorbed On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending to grant a marketing authorisation for the medicinal product IXIARO, containing a target total protein amount of […]
EMEA press release: CHMP adopted a positive opinion for pandemic influenza vaccine H5N1 (Celvapan)
COMMITTEE FOR MEDICINAL PRODUCTS FOR HUMAN USE SUMMARY OF POSITIVE OPINION for CELVAPAN Common Name: Pandemic Influenza Vaccine (H5N1 whole virion, Vero cell derived, inactivated) On 18 December 2008 the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a marketing authorisation for the medicinal product Celvapan, 7.5 […]