This presentation entitled “Applied Pharmacokinetics in the Adult Critically Ill” is oriented to show pharmacokinetics concepts that are relevant to the ICU. Some of them are:
- First pass metabolism
- Patients in whom oral administration should be avoided
- P-glycoprotein (P-gp)
- Relevance of drug distribution in compartments
- Context specific half life
- Cytochrome 450
- Pharmacogenetics