Clinical guidelines on the management of hepatitis B infection
New clinical practice guidelines on the management of hepatitis B were published this year in Annals of Internal Medicine. These guidelines are the result of the latest National Institutes of Health Consensus Development Conference Statement on hepatitis B.
Recommendations and guidelines on prescribing methadone for chronic pain
Methadone has been traditionally used as a drug to treat heroine addiction. In the last few years, it has gained importance as an agent in the treatment of chronic pain. As a result of this, the US Food and Drug administration has started a campaign to raise awareness about the potential risks of using methadone […]
Premixed Insulin Analogues: A Comparison With Other Treatments for Type 2 Diabetes by the AHRQ
Clinical considerations on the use of premixed insulin analogues for type 2 diabetes. Effect on A1c levels, postprandial glucose levels. Comparison with oral diabetes drugs.
NICE recommends sunitinib (Sutent) for the first-line treatment of metastatic renal cancer
NICE (UK) recommends the tyrosine kinase inhibitor sunitinib (Sutent) first line treatment of metastatic renal cell carcinoma. Implications for patients that are on immunotherapy
Updated recommendations on aspirin for cardiovascular disease prevention
Latest 2009 recommendations for the use of aspirin in the prevention of cardiovascular disease. These recommendations were issued by the U.S. Preventive Services Task Force.
Updated SIGN clinical guideline: Pain management in adults with cancer
The Scottish Intercollegiate Guidelines Network (SIGN) updated a clinical guideline entitled “Control of pain in adults with cancer”. An outline of the contents (drug therapy related) in this guideline for the treatment of cancer induced pain include: Principles of pain management: introduction, World Health Organization cancer pain relief programme, using the WHO ladder. Treatment with […]
Antidepressants podcast: comments on the latest ACP clinical guidelines
Essential Evidence Plus, formerly InfoPOEMs is a service by John Wiley and Sons that aims to give physicians succinct medical evidence that will impact in their medical practice. In this podcast Dr. Ebell and Dr. Wilkes (National Public Radio) discuss the POEM that analyzes the ACP guidelines (published in Annals of Internal Medicine) on antidepressants. […]
Evidence based medicine and how to critically read papers. Resources to develop an essential skill
It is essential for us, health proessionals , to learn how to critically interpret scientific information. Many times we will read articles that are absolutely irrelevant, or papers that are markedly biased trying to sell us products (new drugs, medical devices). It is our duty to know how to discern the evidence that should guide […]