Category Archives: Antivirals

Animation: NRTIs mechanism of action

Animation: NRTIs mechanism of action

Nucleoside analog reverse transcriptase inhibitors (NRTIs) are nucleoside analogues that act as competitive inhibitors of HIV-1 reverse transcriptase. As shown in the animation, these drugs compete with nucleoside triphosphates for access to reverse transcriptase. All NRTIs lack a 3-hydroxyl group; thus, their incorporation into a growing DNA chain results in its termination. They require intracytoplasmicContinue Reading

Video lecture on antibiotics and antivirals pharmacology

Brief introduction to the general principles of the pharmacology of infections. Though oriented to a general audience, it is a very interesting and accurate presentation on antibiotics and antivirals. Continue Reading

Study aid for antiviral agents: table summarizing their spectrum of activity

The following images created by the Dept. of Pharmacology at University of Utah are great for reviewing antifungals before a test like USMLE: This table contains the following agents: Trifluridine, Vidarabine, acyclovir, ganciclovir, foscarnet, azt, ddI, ribavirin, amantadine.Continue Reading

Antitubercular and antiviral (HSV, CMV, influenza) drugs: NCLEX video review

This video is targeted to nurses and nursing students, as a pharmacology review previous to the NCLEX exam. It reviews the following drug classes: Antimycobacterial (antitubercular) drugs: isoniazid, pyrazinamide, rifampin, ethambutol Drugs for the treatment of herpesvirus infections: acyclovir famciclovir Drugs for the treatment of influenza:amantadine, rimantadine, zanamivir, oseltamivir Drugs for the treatment of citomegalovirusContinue Reading

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