Animation: NRTIs mechanism of action

Nucleoside analog reverse transcriptase inhibitors (NRTIs) are nucleoside analogues that act as competitive inhibitors of HIV-1 reverse transcriptase. As shown in the animation, these drugs compete with nucleoside triphosphates for access to reverse transcriptase. All NRTIs lack a 3-hydroxyl group; thus, their incorporation into a growing DNA chain results in its termination. They require intracytoplasmic […]

Antitubercular and antiviral (HSV, CMV, influenza) drugs: NCLEX video review

This video is targeted to nurses and nursing students, as a pharmacology review previous to the NCLEX exam. It reviews the following drug classes: Antimycobacterial (antitubercular) drugs: isoniazid, pyrazinamide, rifampin, ethambutol Drugs for the treatment of herpesvirus infections: acyclovir famciclovir Drugs for the treatment of influenza:amantadine, rimantadine, zanamivir, oseltamivir Drugs for the treatment of citomegalovirus […]

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