PowerPoint presentations: antipsychotics (neuroleptics) pharmacology

schizophreniaThis set of PPT presentations is aimed to give an overview on neuroleptics (antipsychotics) through lectures developed by authors with slightly different backgrounds. Most of the PPT files have topics in common, such as: mechanism of action, classification of agents according to potency, differences between first and second generation, side effects profile, among others.

Antipsychotics Review in Primary care. A PPT By Shomir Banerjee, M.D.

Dr. Banerjee discusses the topic from a Family Medicine specialist point of view. Some other resources related to Family Medicine by the same author can be found at Shomir.org.

Presentation outline:

  • Differences between first and second generation antipsychotics.
  • How do typical and atypical Antipsychotics work? Mechanisms of action.
  • Classification by potency.
  • Acute extrapyramidal symptoms with high potency agents ( Akathisia, Dystonia, Parkinsonism).
  • Neuroleptic Malignant Syndrome.
  • Tardive Dyskinesia.
  • Atypical vs Typical Antipsychotics.
  • Are atypicals “better?”
  • Monitoring
  • Analysis of agents: clozapine (Clozaril), olanzapine (Zyprexa), risperidone (Risperdal), quetiapine (Seroquel), ziprasidone (Geodon), aripiprazole (Abilify).

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Conventional Antipsychotics: Concise Review for  Non-Psychiatrists Treating Developmentally Disabled Population. A PPT by S. Christopher Shim, M.D.

Dr. Shim is an American Psychiatric Association Distinguished Fellow who shares his practical approach on conventional antipsychotics with non-psychiatrists.

Presentation outline:

  • Equivalence between high potency agents: Haloperidol, fluphenazine, thiothixine, trifluoperazine, pimozide.
  • Equivalence between low potency agents: thioridazine, chlorpromazine, mesoridazine.
  • Benefits & risks of high and low potency agents.
  • Safety and Tolerability –side effects profile-.
  • EPS (Extra Pyramidal Symptoms): features and treatment.
  • Cardiovascular effects: Malignant Arrhythmias (torsade de pointes), Sudden Cardiac Death
  • Cautions: Reduction or Discontinuation of Conventional Antipsychotic Medications

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Treatment of Schizophrenia (and Related Psychotic Disorders). A PPT by Scott Stroup, MD, MPH.

This presentation explores some of the most relevant clinical features of schizophrenia as well as other psychoses. It also reviews in chronological order of approval some of the most important neuroleptics (both first and second generation). As the presentations shown above, it highlights the most important side effects related to the use of antipsychotic medications. It also focuses on non-pharmacological therapies and other type of interventions .

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