Antiretrovirals drugs: video review for nurses (NCLEX)

This video review covers the medications used for the treatment of HIV infection. The target audience of the review is nursing students and nurses, it covers mainly adverse effects of the different drug classes. More on nursing pharmacology Technorati : HIV, NCLEX, NRTIs,  NNRTI, Nurses & nursing students

P-glycoprotein: animation showing its role in chemotherapy resistance

Some introductory information about MDR1, the protein that mediates resistance to chemotherapeutic agents, from Wikipedia: P-glycoprotein (plasma gycoprotein, abbreviated as P-gp or Pgp) is a well-characterized ABC-transporter of the MDR/TAP subfamily. P-gp is also called ABCB1, ATP-binding cassette sub-family B member 1, MDR1, and PGY1. P-glycoprotein has also recently been designated CD243 (cluster of differentiation 243). […]

Gene Genie #43: Personal genomics, health and evolution

Image credit: Ricardo Vidal at Biotech Once again, PharmaMotion is hosting a blog carnival. This time is the turn of Gene Genie, a carnival dedicated to cover the buzz around the web about genetics (with some orientation to personalized genetics). I hope that PharmaMotion readers find it interesting.. US PharmD compiled an excellent list of […]

Gastrointestinal drugs for nurses

Below is a very good review presentation from NurseReview.org about drugs that affect the gastrointestinal system: 1. Drugs affecting GI secretions 2. Laxatives 3. Anti-diarrheals 4. Emetics and anti-emetics More on nursing pharmacology Technorati : Anti-diarrheals, Anti-emetics, Laxatives, NCLEX, Nurses & nursing students, PPI, pharmacology for nurses

NCLEX pharmacology video review: antibiotics

This video pharmacology review for nurses deals with antibiotics: penicilins, cephalosporins, aminoglycosides, vancomycin and others. Part 2 covers: macrolides, , chloramphenicol, quinolones, and sulfonamides. There is a related animation that explains  linezolid mechanism. More on nursing pharmacology Further reading Gilbert, D; Moellering R (editors) “Sanford Guide to Antimicrobial Therapy”, 39th edition. Antimicrobial therapy: 2009 Hauser, […]

Cochrane review podcast: Commercial spacers as effective as home-made?

Spacers in combination with metered-dose inhalers for delivery of bronchodilator drugs have proved to be effective. However, in some low income areas ( mainly in developing countries) it may not be something affordable or accesible to patients. As a response to this issue, home-made spacers (tipically with plastic bottles) have been widely used. In this Cochane […]

Respiratory drugs for nurses: antihistamines, bronchodilators, antitussives and others

This PowerPoint presentation developed by NurseReview.org summarizes core concepts of the drugs used for treatment of respiratory conditions. Antihistamines Antitussives Decongestants Drugs for COPD: Bronchodilators, inhaled steroids, Leukotriene receptor blockers Expectorants Great pharmacology slides for nurses and nursing students preparing for NCLEX-RN. More on nursing pharmacology

Anticoagulants MCQs for test review

Here are a couple of questions related to the pharmacology of coagulation.  These questions from the UMKC School of Medicine have a different degree of difficulty, but are useful to review the topic.  To get a better understanding on the topic, you can read about  antiplatelet agents and thrombolytic drugs. Item Number: 10968 correct answer: […]

Intravenous and inhalational anesthetics, MCQs for test review

I believe some of the questions ( developed by the UMKC School of Medicine) in this set would be more suitable for an anesthesiologist or anesthesia resident than for a medical student in the pre-clinical years. However, most of them are regular questions from classic pharmacology textbooks. I hope you find them useful. Item Number: correct answer: 2 category: Anesthetics 1. All of the following factors […]

Analgesics (opioids, nsaids): MCQs for pharmacology review

These questions have been created by the Department of Pharmacology, UMKC School of Medicine.  The use I suggest is to review your knowledge of the subject for USMLE or other pharma test.   Did you find them useful? Too hard ? Too easy? Use the comment form to comment what did you think of them! Item Number: 1684 correct answer: 5 category: Analgesics 1. A child has ingested an unknown substance and has evidence of respiratory depression. […]

Video animation: mechanism of ionotropic receptors or ligand-gated ion channels (LGICs)

In pharmacology, receptors can be divided into 4 general groups: 1. Ion channels: Ligand gatedace Voltage gated Second messenger regulated 2. G protein coupled receptors 3. Receptor tyrosine kinase 4. Intracellular hormone receptors: like  the glucocorticoid receptor The video animation below shows the activation of a ionotropic receptor or ligand-gated ion channel (LGIC): An excerpt […]

What means sensitivity in pharmacology? Definition

The following pharmacological definition has been taken from the Pharmacology and Experimental Therapeutics Department Glossary at Boston University School of Medicine. Sensitivity: The ability of a population, an individual or a tissue, relative to the abilities of others, to respond in a qualitatively normal fashion to a particular drug dose. The smaller the dose required […]

EMEA reviewed methylphenidate (Ritalin) for ADHD and issued recommendations for its safer use

EMEA’s Committee for Medicinal Products for Human Use (CHMP) has reviewed methylphenidate for attention deficit/hyperactivity disorder (ADHD). Quoting the press release issued 22 January 2009: The European Medicines Agency (EMEA) has concluded that methylphenidate-containing medicines remain suitable for the treatment of children aged six years or older and adolescents with attention deficit/hyperactivity disorder (ADHD). It has […]

FDA recommendations on clopidogrel (Plavix) because of decreased response and PPI interactions

Pharmamotion has now a new page containing updates on  clopidogrel PPI interactions. The FDA issued today an early communication about an ongoing safety review of the antiplatelet agent clopidogrel bisulfate (Plavix). The backgroung to this is the recent evidence of: A decreased response to clopidogrel in some patients. Since clopidogrel is a prodrug, genetic polymorphisms […]

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