NICE recommends sunitinib (Sutent) for the first-line treatment of metastatic renal cancer
NICE (UK) recommends the tyrosine kinase inhibitor sunitinib (Sutent) first line treatment of metastatic renal cell carcinoma. Implications for patients that are on immunotherapy
Warfarin dosing: the role of genes
Warfarin dosing: the genes VKORC1, CYP2C9, CYP4F2 are determinants in the dosing of warfarin. Role in clinical practice of pharmacogenomics: genetic testing to guide warfarin therapy.
Updated recommendations on aspirin for cardiovascular disease prevention
Latest 2009 recommendations for the use of aspirin in the prevention of cardiovascular disease. These recommendations were issued by the U.S. Preventive Services Task Force.
Embryonic Stem Cells: video animations explaining techniques and therapeutic potential
How Embryonic Stem Cell Lines are Made, Dolan DNA Learning Center. Stem Cells explained: an interactive tutorial, University of Michigan. Animation outline: Definition and importance of Embryonic Stem Cells Cell specialization Adult stem cells: tissue specific stem cells Somatic cell nuclear transfer Stem cells therapy:Cell cultures for drug screening
PowerPoint on neuromuscular blockers pharmacology: mechanism of action, classification, uses, interactions and more
Neuromuscular blockers: mechanism of action, duration,adverse effects, interactions, cla ssification.By the Dpt. of Pharmacology. Univ. of Beirut
How Should Clinicians Consider the Results of a Drug Clinical Trial? PowerPoint on Evidence Based Medicine
Southern Collaboration in Research to Impact Prescription of Therapeutics (SCRIPTS), is a project aimed to”help prescribers enhance their ability to evaluate drug related information to improve their prescribing practices and describe proper prescribing practices to improve quality of patient care”. It is sponsored by University of Alabama at Birmingham. In this module they teach us […]
Podcast: dexamethasone for headache
Essential Evidence Plus, formerly InfoPOEMs is a service by John Wiley and Sons that aims to give physicians succinct medical evidence that will impact in their medical practice. In this podcast Dr. Ebell and Dr. Wilkes (National Public Radio) discuss the POEM titled: “Dexamethasone may prevent headache recurrence after treatment of acute migraine” You can […]
NClEX video review: antifungals pharmacology
Some of the drugs covered are: Amphotericin B, Ketoconazole (Nizoral), griseofulvin, terbinafine “Azole” antifungals: Fluconazole (Diflucan), Itraconazole, Vorconazole, Nystatin, Mycostatin
ACCOMPLISH study reviewed by the National Prescribing Centre
ACCOMPLISH trial analyzed by the NPC team, independent and unbiased information relevant to medical practice.
Review of Embryonic Stem Cells potential: PowerPoint presentations from academia
PowerPoint presentations from academia about Embryonic Stem Cells and their therapeutic potential. Review of medical aspects, scientific and bioethical issues.
FDA: potential risk of HIV and hepatitis transmission when insulin pens and cartridges are shared
An excerpt of FDA’s press release issued 19th March 2009: The U.S. Food and Drug Administration today issued an alert to health care professionals reminding them that single-patient insulin pens and insulin cartridges should not be used to administer medication to multiple patients due to the potential risk of transmitting blood-borne pathogens such as HIV […]
Analysis of antidepressants effectiveness in adolescents: InfoPOEMs podcast
Essential Evidence Plus, formerly InfoPOEMs is a service by John Wiley and Sons that aims to give physicians succinct medical evidence that will impact in their medical practice. In this podcast Dr. Ebell and Dr. Wilkes (National Public Radio) discuss the POEM titled: “Antidepressants only modestly effective for adolescent depression” Listen to the podcast on […]
Carbamazepine (Tegretol) and Stevens-Johnson syndrome: the manufacturer recommends genetic testing
The manufacturer of carbamazepine (Tegretol) updated the drug’s summary of product characteristics: ‘Before deciding to initiate treatment, patients of Han Chinese and Thai origin should whenever possible be screened for HLA-B*1502 as this allele strongly predicts the risk of severe carbamazepine-associated Stevens-Johnson syndrome’ Health Canada warned in March 2008 about carbamazepine’s side effects in […]
More evidence that bisphosphonates do not increase the risk of atrial fibrillation (AF) or flutter
Bisphosphonates don’t increase the risk of atrial fibrillation, according to the study Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety, published in PLoS One on March 2009. The authors used a self-control case series analysis to study nearly 400,000 women from the UK General Practice Research Database. They […]