COGENT trial: no clopidogrel-PPIs interaction
According to the results of the COGENT trial, the combination of the antiplatelet clopidogrel and the PPI omeprazole does not produce clinically relevant cardiovascular interactions.
Blog of the month: Clinical Correlations
This is the first post of a new section that gathers the best educational medical blogs on the web. This month is Clinical Correlations turn, the New York University Internal Medicine Blog. Clinical Correlations is a peer reviewed publication that is written by a team of independent editors. What makes this educational initiative really appealing […]
PowerPoint on general anesthesia and anesthetic agents
Dr. Ravindra S.Beedimani shared one of his PowerPoint lectures with Pharmamotion readers, the topic here is “Pharmacology of general anesthesia”. Dr. Beedimani is Associate Professor in Pharmacology at American University of the Caribbean, School of Medicine, St. Maarten, Netherlands Antilles. If you are interested in contributing to this blog, just send an e-mail to pharmamotion@gmail.com
An excellent animation on the mechanisms of drug addiction
The Genetic Science Learning Center at University of Utah developed an excellent animation depicting the mechanisms of addiction of most drugs of abuse. They use a cartoon-like approach to show biochemical changes in mouse brains.
Ustekinumab for plaque psoriasis approved by FDA
Ustekinumab is a monoclonal antibody that targets IL-12 and IL-23, it is approved for the treatment of plaque psoriasis. Read the latest recommendations on its use.
Vancomycin mechanism of action: an animation
Vancomycin is a tricyclic glycopeptide that has gained clinical importance thanks to its effectiveness against organisms such as MRSA and enterococci. It has activity against Gram-positive rods and cocci, Gram-negative rods are resistant to its bactericidal action. Some clinical uses of IV vancomycin include treatment of infective endocarditis and sepsis caused by MRSA. Since vancomycin […]
Cancer chemotherapy: PPT presentations
The PowerPoint files in this posts have been shared by R. Senthil Kumar M.D. , Dean of Basic Sciences and Pharmacology Professor at St. Matthew’s University School of Medicine. If you are interested in contributing to this blog, just send an e-mail to pharmamotion@gmail.com PPT 1: Introduction to cancer chemotherapy Download PPT file: Cancer Chemotherapy […]
Antiplatelet agents: mechanisms of action and general overview
This post is an overview on antiplatelet drugs, we will focus on the classification of agents and their mechanism of action. The most relevant facts related to therapeutics will also be discussed here, followed by a video review by K.G. Paul, M.D. A related article explores the pharmacology of thrombolytic agents. Classification of antiplatelet agents […]
Serotonin 5-HT3-receptor antagonists: pharmacokinetics, MOA, indications and adverse effects
This posts overviews the general characteristics, pharmacokinetics, mechanism of action, dosing, indications and adverse effects profile of serotonin 5-HT3-receptor antagonists. These drugs are being increasingly used for the prevention of chemotherapy induced nausea and vomiting as well as antiemetic prophylaxis of post-operative and post-radiation nausea and vomiting.
Histamine physiologic effects
Illustrated review of histamine main physiologic actions on inflammation, gastrointestinal secretion, bronchial smooth muscle, among others.
Video: molecular mechanisms of nicotine addiction
This video explains the pathophysiologic changes behind nicotine addiction, it identifies nicotinic acetylcholine receptor as a key protein for the development of dependence.
How to survive your first night on call: PowerPoint presentation
This PowerPoint presentation has great suggestions and tips on how to handle a night on call. It is specially useful for junior physicians and covers real-life clinical situations you may encounter.
Video lecture on antibiotics and antivirals pharmacology
Brief introduction to the general principles of the pharmacology of infections. Though oriented to a general audience, it is a very interesting and accurate presentation on antibiotics and antivirals.
Golimumab (Simponi) side effects: risk of serious fungal infections
Centocor Ortho Biotech and FDA reminded prescribers of the risk of serious fungal infections associated with TNF-α blockers, this includes the newer Simponi (golimumab).