Latest posts
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Video lecture on the management of neuropathic and cancer pain
Mark Wallace, M.D., Director of UCSD’s Center for Pain & Palliative Medicine, updates on current therapies for pain, focusing on neuropathic pain. Overview of pharmacologic and non-pharmacologic management of chronic pain.
Video: What are double blind clinical trials?
“How Double Blind Clinical Trials Are Done” explains in a simple way the scientific methodology behind double blind clinical trials, a key step in the drug development process.
FDA video on erlotinib (Tarceva) adverse effects
FDA video warning on gastrointestinal dermatologic and ophthalmic side effects of erlotinib (Tarceva).
Prasugrel (Effient): mechanism of action, indications and adverse effects
Overview on the mechanism of action, indications, adverse effects profile of prasugrel (Efient in the EU, Effient in the USA). PowerPoint on the TIMI TRITON 38 trial.
Clinical guidelines on the management of hepatitis B infection
New clinical practice guidelines on the management of hepatitis B were published this year in Annals of Internal Medicine. These guidelines are the result of the latest National Institutes of Health Consensus Development Conference Statement on hepatitis B.
Video lecture: Biologic therapies for inflammatory and autoimmune diseases
Dr. Chan explains how biologic therapy (mainly through monoclonal antibodies) is changing the present and future of autoimmune and inflammatory diseases. He illustrates some examples of autoimmune diseases such as: multiple sclerosis, asthma, treatment of rheumatoid arthritis with etanercept, and others.
Pregabalin (Lyrica) not approved for fibromyalgia by the EMEA
EMEA didn’t approve treatment of fibromyalgia as a new indication for pregabalin (Lyrica).The CHMP was concerned that the benefits of Lyrica in fibromyalgia had not been shown in either the short or the long term.
Rituximab (Rituxan, MabThera): first line treatment for chronic lymphocytic leukemia
The UK’s National Institute for Health and Clinical Excellence (NICE) issued yesterday a guidance on the use of rituximab as first line treatment for chronic lymphocytic leukemia.
Rubefacients for acute and chronic pain. Podcast review by The Cochrane Collaboration
Andrew Moore, from the Nuffield Department of Anaesthetics at the University of Oxford, discusses the available evidence on the use of rubefacients for acute and chronic pain.
PowerPoint presentations: antipsychotics (neuroleptics) pharmacology
PPT files on antipsychotics (neuroleptics): it gathers lectures from different specialties (Family Medicine, Psychiatry) highlighting key pharmacological pearls.
NSAIDs: PowerPoint presentations
This set of lectures intends to overview the most relevant points in NSAIDs pharmacology. Troughout the post, some points are repeated. These are key concepts to remember, such as: mechanism of action, indications, some chemical characteristics and side effects profile (mainly renal and gastrointestinal).
Video on Botulinum toxin type A (Botox) mechanism of action
Video animation showing the mechanism of action of Botox (Botulinum toxin type A) on neuromuscular neurotransmission.
PPIs reduce the effectiveness of clopidogrel (Plavix)
Pharmamotion has now a new page containing updates on clopidogrel – PPI interactions. The latest edition of the monthly newsletter from the Medicines and Healthcare products Regulatory Agency has issued a drug safety advice on the interaction between the antiplatelet drug clopidogrel (Plavix) and PPIs. They conclude that available data supports a clinically significant interaction
Brief Grand Rounds from Argentina
I’m starting this Grand Rounds with a confession: I completely suffered of lack of time for this Round’s preparation. Maybe you are wondering why, since this blog carnival is perfectly scheduled. Well, the thing is that here in Argentina winter has arrived and things are starting to get a bit more complicated than we thought.
Methamphetamine mechanism of addiction in the brain reward system
A video by National Geographic discusses the mechanisms of addiction of Methamphetamine (also known as Meth and Tik).