Beta lactams antibiotics (penicillins and cephalosporins) mechanism of action: videos and animations

Mechanism of action of the beta lactam antibiotics (penicillins and cephalosporins) The beta-lactam antibiotics can kill susceptible bacteria. Although knowledge of the mechanism of this action is incomplete, numerous researchers have supplied information that allows understanding of the basic phenomenon (seeGhuysen, 1991; Bayles, 2000). The cell walls of bacteria are essential for their normal growth […]

Cisplatin mechanism of action: 3-D video animation

Mechanism of Action. Cisplatin, carboplatin, and oxaliplatin enter cells by diffusion, and by an active Cu2+ transporter (Kruh, 2003). Inside the cell, the chloride atoms of cisplatin may be displaced and the compound may be inactivated directly by reaction with nucleophiles such as thiols. Chloride is replaced by water, yielding a positively charged molecule. In […]

G protein-coupled receptors: 3-D video and text

G protein-coupled receptors are the most abundant class of receptors in the human body. These receptors are exposed at the extracellular surface of the cell membrane, traverse the membrane, and possess intracellular regions that activate a unique class of signaling molecules called G proteins. (G proteins are so named because they bind the guanine nucleotides […]

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