Pharmacology Corner

Pharmacology CME for physicians, pharmacists and nurses.

Methamphetamine mechanism of addiction in the brain reward system

methamphetamine_moa The following video by National Geographic discusses the mechanisms of addiction of Methamphetamine (also known as Meth and Tik).

It is oriented to a general audience. However, it’s useful to review the brain reward system and some important dopamine pathways.

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Further reading

Addiction, Dopamine, and the Molecular Mechanisms of Memory. Neuron, Vol. 25, 515–532, March, 2000. Free Full Text – PDF -

Is there a common molecular pathway for addiction? EJ Nestler – Nature neuroscience, 2005.  Free Full Text – PDF -

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