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How Should Clinicians Consider the Results of a Drug Clinical Trial? PowerPoint on Evidence Based Medicine
Southern Collaboration in Research to Impact Prescription of Therapeutics (SCRIPTS), is a project aimed to”help prescribers enhance their ability to evaluate drug related information to improve their prescribing practices and describe proper prescribing practices to improve quality of patient care”. It is sponsored by University of Alabama at Birmingham. In this module they teach us
Podcast: dexamethasone for headache
Essential Evidence Plus, formerly InfoPOEMs is a service by John Wiley and Sons that aims to give physicians succinct medical evidence that will impact in their medical practice. In this podcast Dr. Ebell and Dr. Wilkes (National Public Radio) discuss the POEM titled: “Dexamethasone may prevent headache recurrence after treatment of acute migraine” You can
NClEX video review: antifungals pharmacology
Some of the drugs covered are: Amphotericin B, Ketoconazole (Nizoral), griseofulvin, terbinafine “Azole” antifungals: Fluconazole (Diflucan), Itraconazole, Vorconazole, Nystatin, Mycostatin
ACCOMPLISH study reviewed by the National Prescribing Centre
ACCOMPLISH trial analyzed by the NPC team, independent and unbiased information relevant to medical practice.
Review of Embryonic Stem Cells potential: PowerPoint presentations from academia
PowerPoint presentations from academia about Embryonic Stem Cells and their therapeutic potential. Review of medical aspects, scientific and bioethical issues.
FDA: potential risk of HIV and hepatitis transmission when insulin pens and cartridges are shared
An excerpt of FDA’s press release issued 19th March 2009: The U.S. Food and Drug Administration today issued an alert to health care professionals reminding them that single-patient insulin pens and insulin cartridges should not be used to administer medication to multiple patients due to the potential risk of transmitting blood-borne pathogens such as HIV
Analysis of antidepressants effectiveness in adolescents: InfoPOEMs podcast
Essential Evidence Plus, formerly InfoPOEMs is a service by John Wiley and Sons that aims to give physicians succinct medical evidence that will impact in their medical practice. In this podcast Dr. Ebell and Dr. Wilkes (National Public Radio) discuss the POEM titled: “Antidepressants only modestly effective for adolescent depression” Listen to the podcast on
Carbamazepine (Tegretol) and Stevens-Johnson syndrome: the manufacturer recommends genetic testing
The manufacturer of carbamazepine (Tegretol) updated the drug’s summary of product characteristics: ‘Before deciding to initiate treatment, patients of Han Chinese and Thai origin should whenever possible be screened for HLA-B*1502 as this allele strongly predicts the risk of severe carbamazepine-associated Stevens-Johnson syndrome’ Health Canada warned in March 2008 about carbamazepine’s side effects in
More evidence that bisphosphonates do not increase the risk of atrial fibrillation (AF) or flutter
Bisphosphonates don’t increase the risk of atrial fibrillation, according to the study Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety, published in PLoS One on March 2009. The authors used a self-control case series analysis to study nearly 400,000 women from the UK General Practice Research Database. They
FDA video warning about local anesthetics side effects
Local anesthetics side effects are covered in the March 2009 edition of FDA’s Patient Safety News. The agency’s concern is that after a study published in the the journal Radiology in which the authors suggest the use of topical anesthetics to reduce disconfort during mammography, more and more women will start using them without being
Drugs for migraine prophylaxis. Which is your choice?
Review of drugs indicated in migraine prophylaxis: beta-adrenergic blockers, calcium channel blockers and tricyclic antidepressants. Clinical guidelines on migraine management.
Respiratory drugs table: pharmacology of asthma and COPD
The Dept. of Pharmacology at University of Utah posted in their website tables to review respiratory pharmacology. This study aid analizes therapeutic uses & specificity, toxicity and side effects of the following drug classes: Bronchodilators: epinephrine, Ephedrine, Isoproterenol, Terbutaline, Isoetharine, Ipratropium bromide, Theophylline, Aminophylline. Leukotriene D4 receptors antagonists:Zafirlukast, Zileutron. Inhibition of mast cell degranulation: Cromolyn
PowerPoint presentation on diuretics: MOA, indications, side effects and therapeutic considerations
The following set of lectures has been created by Dr. Edwin Jackson and were published in the Division for Cardiovascular Pharmacology, a branch of the American Society for Pharmacology and Experimental Therapeutics (ASPET). Part 1: How diuretics work Download: DIURETICS Part 1 – How they work. PPT file Part 2: What do diuretics do Na-K-2Cl
NPS recommendations for the use of valsartan (Diovan)
The National Prescribing Service Limited (Australia) issues a publication called NPS RADAR. In this issue valsartan (Diovan) is reviewed, this is the summary: Valsartan reduces blood pressure to a similar extent as other angiotensin II-receptor antagonists. If blood pressure is not controlled by valsartan 160 mg, add a second drug rather than increasing the dose
NPS: Desvenlafaxine (Pristiq) not superior to venlafaxine for major depressive disorder
The National Prescribing Service Limited (Australia) made an independent evaluation on the role of desvenlafaxine (Pristiq) for the treatment of major depressive disorder. Summary: Desvenlafaxine is the active metabolite of venlafaxine. There is no evidence that desvenlafaxine is more effective, safer or better tolerated than venlafaxine or other antidepressants. Doses above 50 mg/day are unlikely