Digoxin Mechanism of Action: Animated Tutorial
Mechanism of action of digoxin (Lanoxin) reviewed: animation and excerpts of a pharmacology textbook on the pharmacological effects of this cardiac glycoside for heart failure.
PowerPoint on neuromuscular blockers pharmacology: mechanism of action, classification, uses, interactions and more
Neuromuscular blockers: mechanism of action, duration,adverse effects, interactions, cla ssification.By the Dpt. of Pharmacology. Univ. of Beirut
NClEX video review: antifungals pharmacology
Some of the drugs covered are: Amphotericin B, Ketoconazole (Nizoral), griseofulvin, terbinafine “Azole” antifungals: Fluconazole (Diflucan), Itraconazole, Vorconazole, Nystatin, Mycostatin
PowerPoint presentation on diuretics: MOA, indications, side effects and therapeutic considerations
The following set of lectures has been created by Dr. Edwin Jackson and were published in the Division for Cardiovascular Pharmacology, a branch of the American Society for Pharmacology and Experimental Therapeutics (ASPET). Part 1: How diuretics work Download: DIURETICS Part 1 – How they work. PPT file Part 2: What do diuretics do Na-K-2Cl […]
Study aids for antifungals pharmacology: diagram showing MOA and table summary for activity spectrum
The following images created by the Dept. of Pharmacology at University of Utah are great for reviewing antifungals before a test like USMLE: Diagram of sites of action of major antifungals Table: Spectrum of activity of antifungal agents Agents: Amphotericin, nystatin, flucytosine, azoles: miconazole, ketoconazole, itraconazole, fluconazole, griseofulvin Technorati : Antifungals, mechanism of action, tables
PowerPoint presentation: ACE inhibitors, ARBs, and calcium channel blockers
The following pharmacology PowerPoint has been developed by Ed Sheridan, Pharm.D. Outline: ACE inhibitors, Angiotensin II Receptor Blockers (ARBs), and calcium channel blockers •Review the Mechanism of Action •Review Safety •Review Efficacy •Hypertension Download ppt slides: pharmacology of ACEi, ARBs, and Calcium channel blockers. You may also find interesting related PowerPoint presentation on drug therapy […]
Vorinostat MSD for cutaneous T-cell lymphoma. MSD withdraws marketing application
Excerpts from the EMEA press release (dated 17th February) on the withdrawal of the marketing application for Vorinostat MSD: The European Medicines Agency (EMEA) has been formally notified by Merck Sharp & Dohme Ltd of its decision to withdraw its application for a centralised marketing authorisation for the medicine Vorinostat MSD (vorinostat), 100 mg hard […]
Animation on the mechanism of action of GnRH agonists and antagonists in the treatment of prostate cancer
The video animations below depict the mechanism of action of GnRH agonists and antagonists in the treatment of prostate cancer. The three movies will start playing at the same time, you can right-click on each of them and deselect “play” in case you want to stop any of them. This excerpt from the Wikipedia article […]
Animation on histamine release and antihistamines mechanism of action
In this 3-D animation, oriented to the general public, we can see the process of histamine release by mast cell starting from the exposure to the allergen: This image shows the same process: H1 blockers are a class of widely prescribed drugs, here an excerpt of its pharmacodynamics (Source: Katzung’s Basic and Clinical Pharmacology) A. […]
P-glycoprotein: animation showing its role in chemotherapy resistance
Some introductory information about MDR1, the protein that mediates resistance to chemotherapeutic agents, from Wikipedia: P-glycoprotein (plasma gycoprotein, abbreviated as P-gp or Pgp) is a well-characterized ABC-transporter of the MDR/TAP subfamily. P-gp is also called ABCB1, ATP-binding cassette sub-family B member 1, MDR1, and PGY1. P-glycoprotein has also recently been designated CD243 (cluster of differentiation 243). […]
Video animation: mechanism of ionotropic receptors or ligand-gated ion channels (LGICs)
In pharmacology, receptors can be divided into 4 general groups: 1. Ion channels: Ligand gatedace Voltage gated Second messenger regulated 2. G protein coupled receptors 3. Receptor tyrosine kinase 4. Intracellular hormone receptors: like the glucocorticoid receptor The video animation below shows the activation of a ionotropic receptor or ligand-gated ion channel (LGIC): An excerpt […]
Linezolid (an oxazolidinone): mechanism of action animation
This animation depicts the mechanism of action of linezolid (Zyvox): Further reading Gilbert, D; Moellering R (editors) “Sanford Guide to Antimicrobial Therapy”, 39th edition. Antimicrobial therapy: 2009 Hauser, A. “Antibiotic Basics for Clinicians: Choosing the Right Antibacterial Agent”.1st edition. LWW:2007 Gallagher, J. “Antibiotics Simplified”. 1st edition. Jones & Bartlett Publishers: 2008
Animation of thiazolidinediones (TZDs) and fibrates mechanism of action. PPAR activation movie
This excellent animation from the Hybrid team shows in detail the process of activation of the PPAR receptor, its interaction with the RXR and the ligand. This animation is an excellent oportunity to review the drugs that act as ligands of the PPAR receptor and its subtypes (Alpha and Gamma). Novel agents that target PPAR […]
Mechanism of action video animation: ACE inhibitors, Angiotensin II receptor blockers (ARBs) and the Renin Angiotensin Aldosterone System
Also, a diagram of the Renin Angiotensin Aldosterone System (RAAS System) physiology. Drugs acting on the Renin Angiotensin Aldosterone System. ACE Inhibitors. List of agents Sulfhydryl-containing agents Captopril (Capoten), Zofenopril Dicarboxylate-containing agents Enalapril (Vasotec, Renitec) Ramipril (Altace, Tritace, Ramace, Ramiwin) Quinapril (Accupril) Perindopril (Coversyl, Aceon) Lisinopril (Lisodur, Lopril, Novatec, Prinivil, Zestril) Benazepril (Lotensin) Phosphonate-containing agents […]